The mitochondrial permeability transition: Recent progress and open questions
Major progress has been made in defining the basis of the mitochondrial permeability
transition, a Ca2+‐dependent permeability increase of the inner membrane that has puzzled …
transition, a Ca2+‐dependent permeability increase of the inner membrane that has puzzled …
[HTML][HTML] ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: Regulator of metabolism in development and degeneration
The mitochondrial permeability transition pore (mPTP) or mitochondrial megachannel is
arguably one of the most mysterious phenomena in biology today. mPTP has been at the …
arguably one of the most mysterious phenomena in biology today. mPTP has been at the …
Structure of the dimeric ATP synthase from bovine mitochondria
TE Spikes, MG Montgomery… - Proceedings of the …, 2020 - National Acad Sciences
The structure of the dimeric ATP synthase from bovine mitochondria determined in three
rotational states by electron cryo-microscopy provides evidence that the proton uptake from …
rotational states by electron cryo-microscopy provides evidence that the proton uptake from …
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Mitochondrial ATP synthase is vital not only for cellular energy production but also for
energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak …
energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak …
ATP synthase c-subunit leak causes aberrant cellular metabolism in fragile X syndrome
Loss of the gene (Fmr1) encoding Fragile X mental retardation protein (FMRP) causes
increased mRNA translation and aberrant synaptic development. We find neurons of the …
increased mRNA translation and aberrant synaptic development. We find neurons of the …
Impact of engineering the ATP synthase rotor ring on photosynthesis in tobacco chloroplasts
The chloroplast ATP synthase produces the ATP needed for photosynthesis and plant
growth. The trans-membrane flow of protons through the ATP synthase rotates an oligomeric …
growth. The trans-membrane flow of protons through the ATP synthase rotates an oligomeric …
ATP synthase FOF1 structure, function, and structure-based drug design
ATP synthases are unique rotatory molecular machines that supply biochemical reactions
with adenosine triphosphate (ATP)—the universal “currency”, which cells use for synthesis …
with adenosine triphosphate (ATP)—the universal “currency”, which cells use for synthesis …
Raman scattering: from structural biology to medical applications
This is a review of relevant Raman spectroscopy (RS) techniques and their use in structural
biology, biophysics, cells, and tissues imaging towards development of various medical …
biology, biophysics, cells, and tissues imaging towards development of various medical …
I-Shaped Dimers of a Plant Chloroplast FOF1-ATP Synthase in Response to Changes in Ionic Strength
F-type ATP synthases play a key role in oxidative and photophosphorylation processes
generating adenosine triphosphate (ATP) for most biochemical reactions in living …
generating adenosine triphosphate (ATP) for most biochemical reactions in living …
Structural basis of redox modulation on chloroplast ATP synthase
In higher plants, chloroplast ATP synthase has a unique redox switch on its γ subunit that
modulates enzyme activity to limit ATP hydrolysis at night. To understand the molecular …
modulates enzyme activity to limit ATP hydrolysis at night. To understand the molecular …