Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
OP Kallioniemi, A Kallioniemi, J Piper… - Genes …, 1994 - Wiley Online Library
Comparative genomic hybridization (CGH) is a powerful new method for molecular
cytogenetic analysis of cancer. In a single hybridization, CGH provides an overview of DNA …
cytogenetic analysis of cancer. In a single hybridization, CGH provides an overview of DNA …
The new cytogenetics: blurring the boundaries with molecular biology
MR Speicher, NP Carter - Nature reviews genetics, 2005 - nature.com
Exciting advances in fluorescence in situ hybridization and array-based techniques are
changing the nature of cytogenetics, in both basic research and molecular diagnostics …
changing the nature of cytogenetics, in both basic research and molecular diagnostics …
Karyoty** human chromosomes by combinatorial multi-fluor FISH
MR Speicher, SG Ballard, DC Ward - Nature genetics, 1996 - nature.com
We have developed epifluorescence filter sets and computer software for the detection and
discrimination of 27 different DNA probes hybridized simultaneously. For karyotype analysis …
discrimination of 27 different DNA probes hybridized simultaneously. For karyotype analysis …
A faster circular binary segmentation algorithm for the analysis of array CGH data
ES Venkatraman, AB Olshen - Bioinformatics, 2007 - academic.oup.com
Motivation: Array CGH technologies enable the simultaneous measurement of DNA copy
number for thousands of sites on a genome. We developed the circular binary segmentation …
number for thousands of sites on a genome. We developed the circular binary segmentation …
A Kallioniemi, OP Kallioniemi, J Piper… - Proceedings of the …, 1994 - National Acad Sciences
Comparative genomic hybridization was applied to 5 breast cancer cell lines and 33 primary
tumors to discover and map regions of the genome with increased DNA-sequence copy …
tumors to discover and map regions of the genome with increased DNA-sequence copy …