Changes in delta‐9‐tetrahydrocannabinol (THC) and cannabidiol (CBD) concentrations in cannabis over time: systematic review and meta‐analysis

TP Freeman, S Craft, J Wilson, S Stylianou… - …, 2021 - Wiley Online Library
Background and aims Cannabis products with high delta‐9‐tetrahydrocannabinol (THC)
concentrations carry an increased risk of addiction and mental health disorders, while it has …

Effects of cannabis use on human behavior, including cognition, motivation, and psychosis: a review

ND Volkow, JM Swanson, AE Evins, LE DeLisi… - JAMA …, 2016 - jamanetwork.com
With a political debate about the potential risks and benefits of cannabis use as a backdrop,
the wave of legalization and liberalization initiatives continues to spread. Four states …

Does cannabidiol make cannabis safer? A randomised, double-blind, cross-over trial of cannabis with four different CBD: THC ratios

A Englund, D Oliver, E Chesney, L Chester… - …, 2023 - nature.com
As countries adopt more permissive cannabis policies, it is increasingly important to identify
strategies that can reduce the harmful effects of cannabis use. This study aimed to determine …

Association of cannabis with cognitive functioning in adolescents and young adults: a systematic review and meta-analysis

JC Scott, ST Slomiak, JD Jones, AFG Rosen… - JAMA …, 2018 - jamanetwork.com
Importance Substantial shifts in perception and policy regarding cannabis have recently
occurred, with use of cannabis increasing while its perceived harm decreases. One possible …

[HTML][HTML] Cannabidiol as a potential treatment for anxiety disorders

EM Blessing, MM Steenkamp, J Manzanares… - …, 2015 - Elsevier
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …

Acute and chronic effects of cannabinoids on human cognition—a systematic review

SJ Broyd, HH Van Hell, C Beale, M Yuecel… - Biological psychiatry, 2016 - Elsevier
Cannabis use has been associated with impaired cognition during acute intoxication as well
as in the unintoxicated state in long-term users. However, the evidence has been mixed and …

Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

O Devinsky, MR Cilio, H Cross, J Fernandez‐Ruiz… - …, 2014 - Wiley Online Library
To present a summary of current scientific evidence about the cannabinoid, cannabidiol
(CBD) with regard to its relevance to epilepsy and other selected neuropsychiatric disorders …

How does cannabidiol (CBD) influence the acute effects of delta-9-tetrahydrocannabinol (THC) in humans? A systematic review

AM Freeman, K Petrilli, R Lees, C Hindocha… - Neuroscience & …, 2019 - Elsevier
The recent liberalisation of cannabis regulation has increased public and scientific debate
about its potential benefits and risks. A key focus has been the extent to which cannabidiol …

Keep off the grass? Cannabis, cognition and addiction

HV Curran, TP Freeman, C Mokrysz… - Nature Reviews …, 2016 - nature.com
In an increasing number of states and countries, cannabis now stands poised to join alcohol
and tobacco as a legal drug. Quantifying the relative adverse and beneficial effects of …

Are cannabidiol and Δ9‐tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review

JM McPartland, M Duncan, V Di Marzo… - British journal of …, 2015 - Wiley Online Library
Based upon evidence that the therapeutic properties of C annabis preparations are not
solely dependent upon the presence of Δ9‐tetrahydrocannabinol (THC), pharmacological …