In the area of parenteral controlled release formulations, in situ forming implants (ISFI) are
attractive alternatives to preformed implants and microparticles. ISFI avoid the use of large …

In situ forming implants (ISI) based on phase separation by solvent exchange represent an
attractive alternative to conventional preformed implants and microparticles for parenteral …

Effective healing of skin wounds is essential for our survival. Although skin has strong
regenerative potential, dysfunctional and disfiguring scars can result from aberrant wound …

In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

The combination of liposomes with polymeric scaffolds could revolutionize the current state
of drug delivery technology. Although liposomes have been extensively studied as a …

The excellent properties of polyesters combined with their ease of synthesis and
modification enabled their wide use in the pharmaceutical industry. This has been translated …

Peptide and protein drugs with therapeutic effects suffer from their short half-life and low
stability, albeit their high efficiency and specificity. To overcome these demerits, long-acting …

In situ forming (ISF) drug delivery implants have gained tremendous levels of interest over
the last few decades. This is due to their wide range of biomedical applications such as in …

The present study focuses on the development of an effective topical nanogel formulation of
two anti-psoriatic drugs; Acitretin (Act) and Aloe-emodin (AE) using natural polymer chitin …

This paper presents the in vitro and in vivo degradation of BEPO, a marketed in situ forming
depot technology used for the formulation of long-acting injectables. BEPO is composed of a …