Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential
M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023 - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …
COVID-19 impacts on child and youth anxiety and depression: challenges and opportunities
As a result of the COVID-19 pandemic, disaster psychiatry is becoming a core component of
work for mental health professionals around the world. It requires a new flexibility in how we …
work for mental health professionals around the world. It requires a new flexibility in how we …
Childhood adversity and neural development: A systematic review
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …
Early adversity and critical periods: neurodevelopmental consequences of violating the expectable environment
It is now widely recognized that children exposed to adverse life events in the first years of
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As …
life are at increased risk for a variety of neural, behavioral, and psychological sequelae. As …
Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for develo** …
nervous-system development, health, and behavior is critically important for develo** …
A shifting role of thalamocortical connectivity in the emergence of cortical functional organization
The cortical patterning principle has been a long-standing question in neuroscience, yet
how this translates to macroscale functional specialization in the human brain remains …
how this translates to macroscale functional specialization in the human brain remains …
Hidden talents in harsh environments
Although early-life adversity can undermine healthy development, children growing up in
harsh environments may develop intact, or even enhanced, skills for solving problems in …
harsh environments may develop intact, or even enhanced, skills for solving problems in …
Advocacy for improving nutrition in the first 1000 days to support childhood development and adult health
SJ Schwarzenberg, MK Georgieff, S Daniels… - …, 2018 - publications.aap.org
Advocacy for Improving Nutrition in the First 1000 Days to Support Childhood Development
and Adult Health | Pediatrics | American Academy of Pediatrics Skip to Main Content …
and Adult Health | Pediatrics | American Academy of Pediatrics Skip to Main Content …
Biological embedding of childhood adversity: from physiological mechanisms to clinical implications
Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …
maltreatment, caregiver stress or depression, and domestic or community violence, have …
Systematic review of pediatric health outcomes associated with childhood adversity
DL Oh, P Jerman, S Silvério Marques, K Koita… - BMC pediatrics, 2018 - Springer
Background Early detection of and intervention in childhood adversity has powerful potential
to improve the health and well-being of children. A systematic review was conducted to …
to improve the health and well-being of children. A systematic review was conducted to …