[HTML][HTML] Considerations when choosing high-fat, high-fructose, and high-cholesterol diets to induce experimental nonalcoholic fatty liver disease in laboratory animal …

S Radhakrishnan, SF Yeung, JY Ke… - Current developments in …, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is intricately linked to metabolic disease (including
obesity, glucose intolerance, and insulin resistance) and encompasses a spectrum of …

Uptake of Plasmodium chabaudi hemozoin drives Kupffer cell death and fuels superinfections

IC Hirako, MM Antunes, RM Rezende… - Scientific Reports, 2022 - nature.com
Kupffer cells (KCs) are self-maintained tissue-resident macrophages that line liver sinusoids
and play an important role on host defense. It has been demonstrated that upon infection or …

High-fat diet increases mortality and intensifies immunometabolic changes in septic mice

SV Gomes, BV Dias, PAM Júnior, RR Pereira… - The Journal of …, 2023 - Elsevier
Immunometabolic changes in the liver and white adipose tissue caused by high-fat (HF) diet
intake may worse metabolic adaptation and protection against pathogens in sepsis. We …

[HTML][HTML] Physiological accumulation of lipid droplets in the newborn liver during breastfeeding is driven by TLR4 ligands

WF da Silva Júnior, KM de Oliveira Costa… - Journal of Lipid …, 2025 - Elsevier
The liver plays a central role in fat storage, but little is known about physiological fat
accumulation during early development. Here we investigated a transient surge in hepatic …

A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a choline-deficient, methionine-lowered, L-amino acid …

N Suzuki-Kemuriyama, A Abe, K Uno, S Ogawa… - Lipids in Health and …, 2020 - Springer
Background Nonalcoholic steatohepatitis (NASH) is a form of liver disease characterized by
steatosis, necroinflammation, and fibrosis, resulting in cirrhosis and cancer. Efforts have …

Histologická analýza vybraných markerů u kardiometabolických onemocnění 1

K Bůtorová - 2023 - dspace.cuni.cz
Nealkoholové ztučnění jater (NAFLD) je stav definovaný akumulací přebytečného tuku v
játrech, který není doprovázen nadměrnou konzumací alkoholu. V prvním stadiu dochází k …

A sinalização do Receptor de Toll 4 nos hepatócitos, e não no sistema imune, é a principal via para alterações metabólicas hepáticas durante a Endotoxemia

HM de Castro Oliveira - 2022 - repositorio.ufmg.br
RESUMO O fígado é o principal órgão metabólico do corpo, e os hepatócitos–unidades
funcionais responsáveis pelo metabolismo hepático de carboidratos, lipídios, xenobióticos …

Efeito do óleo de milho no metabolismo lipídico e estresse oxidativo em camundongos alimentados com dieta hiperlipídica e rica em frutose

RYO Silva - 2021 - teses.usp.br
Introdução: A doença hepática gordurosa não alcoólica (DHGNA) é o acúmulo de gordura
nos hepatócitos, e seu desenvolvimento e progressão são causados por fatores ambientais …

[PDF][PDF] Efeito do óleo de milho no metabolismo lipídico e estresse oxidativo em camundongos alimentados com dieta hiperlipídica e rica em frutose

RY de Oliveira Silva - 2021 - scholar.archive.org
RESUMO SILVA, Raissa Yolanda de Oliveira. Efeito do óleo de milho no metabolismo
lipídico e estresse oxidativo em camundongos alimentados com dieta hiperlipídica e rica em …

[PDF][PDF] RESEARCH DIETS FOCUS

S Radhakrishnan, M Pellizzon - researchdiets.com
NAFLD spectrum NAFLD spectrum including steatosis, steatohepa s with fibrosis, and
cirrhosis in~ 30 weeks with a NAS score of 5.2 [5, 6]. This diet also induced metabolic …