Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery

J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang… - Bioorganic …, 2022 - Elsevier
Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

Anti-inflammatory drugs and herbs with special emphasis on herbal medicines for countering inflammatory diseases and disorders-a review

MI Yatoo, A Gopalakrishnan, A Saxena… - Recent patents on …, 2018 - benthamdirect.com
Background: Diseases with inflammatory etiopathology have increased in incidence in
recent times. Drugs used for therapeutic management of such inflammatory diseases are …

[HTML][HTML] Sesquiterpene lactones: Promising natural compounds to fight inflammation

MS Matos, JD Anastácio, C Nunes dos Santos - Pharmaceutics, 2021 - mdpi.com
Inflammation is a crucial and complex process that reestablishes the physiological state after
a noxious stimulus. In pathological conditions the inflammatory state may persist, leading to …

[HTML][HTML] An overview of NRF2-activating compounds bearing α, β-unsaturated moiety and their antioxidant effects

MC Egbujor, B Buttari, E Profumo… - International Journal of …, 2022 - mdpi.com
The surge of scientific interest in the discovery of Nuclear Factor Erythroid 2 (NFE2)-Related
Factor 2 (NRF2)-activating molecules underscores the importance of NRF2 as a therapeutic …

Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets

Y Guo, X Peng, F Liu, Q Zhang, L Ding, G Li… - Archives of Pharmacal …, 2024 - Springer
A balance between the development and suppression of inflammation can always be found
in the body. When this balance is disturbed, a strong inflammatory response can damage …

Human disorders associated with inflammation and the evolving role of natural products to overcome

N Kishore, P Kumar, K Shanker, AK Verma - European journal of medicinal …, 2019 - Elsevier
Inflammation is a biological function which triggered after the mechanical tissue disruption or
from the responses by the incidence of physical, chemical or biological negotiator in body …

Chemical Profile and Antioxidant, Anti-Inflammatory, Antimutagenic and Antimicrobial Activities of Geopropolis from the Stingless Bee Melipona orbignyi

HF Santos, JF Campos, CM Santos… - International journal of …, 2017 - mdpi.com
Geopropolis is a resin mixed with mud, produced only by stingless bees. Despite being
popularly known for its medicinal properties, few scientific studies have proven its biological …

Inhibitory effects of cynaropicrin on human melanoma progression by targeting MAPK, NF‐κB, and Nrf‐2 signaling pathways in vitro

P De Cicco, R Busà, G Ercolano… - Phytotherapy …, 2021 - Wiley Online Library
Malignant melanoma is the deadliest skin cancer, due to its propensity to metastasize.
MAPKs and NF‐κB pathways are constitutively activated in melanoma and promote cell …

Chemical composition, antioxidant activity, and milk-clotting activity of aqueous extracts from leaves, stems, and flowers of three tunisian ecotypes of spontaneous and …

R Kouki, I Essaidi, K Annabi, N Dhen, F Haouala… - Agronomy, 2024 - mdpi.com
This study aimed to compare the chemical composition of aqueous extracts from different
aerial plant parts (leaves, stems, and flowers) of Onopordum nervosum ssp. platylepis …

Influence of different extraction techniques on the chemical profile and biological properties of Anthemis cotula L.: Multifunctional aspects for potential pharmaceutical …

S Sut, S Dall'Acqua, G Zengin, I Senkardes… - … of pharmaceutical and …, 2019 - Elsevier
The phytochemical composition of different extracts obtained from stinking chamomile
(Anthemis cotula L.) was investigated. Ethanol was used as solvent and accelerated solvent …