Highlights•There are several promising techniques for processing calcium imaging
data.•Comparing the accuracy of these methods is difficult, due to lack of ground truth.•The …

Highlights•Modern recording technologies are creating data at a scale and complexity that
demand rigorous data analytical approaches.•Neural data science is an essential bridge …

Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

In vivo two-photon calcium imaging is a powerful approach in neuroscience. However,
processing two-photon calcium imaging data is computationally intensive and time …

Miniature microscopes have gained considerable traction for in vivo calcium imaging in
freely behaving animals. However, extracting calcium signals from raw videos is a …

Calcium imaging records large-scale neuronal activity with cellular resolution in vivo.
Automated, fast, and reliable active neuron segmentation is a critical step in the analysis …

Optical microscopy methods such as calcium and voltage imaging enable fast activity
readout of large neuronal populations using light. However, the lack of corresponding …

Fluorescent genetically encoded calcium indicators and two-photon microscopy help
understand brain function by generating large-scale in vivo recordings in multiple animal …

To advance the measurement of distributed neuronal population representations of targeted
motor actions on single trials, we developed an optical method (COSMOS) for tracking …

Advances in optical and electrophysiological recording technologies have made it possible
to record the dynamics of thousands of neurons, opening up new possibilities for interpreting …