The uridine modifications pseudouridine (Ψ), dihydrouridine, and 5-methyluridine are
present in eukaryotic mRNAs. Many uridine-modifying enzymes are associated with human …

Abstract N6-methyladenosine (m6A) is one of the most prevalent internal reversible
chemical modification of RNAs in eukaryotes, which has attracted widespread attention …

RNA pseudouridylation, a dynamic and reversible post‐transcriptional modification found in
diverse RNA species, is crucial for various biological processes, including tRNA …

RNA modifications affect key stages of the RNA life cycle, including splicing, export, decay,
and translation. Epitranscriptomic regulations therefore significantly influence cellular …

The stability of RNA is a critical factor in determining its functionality and degradation in the
cell. In recent years, it has been shown that the stability of RNA depends on a complex …

Abstract N6-methyladenosine (m6A) plays a pivotal role in regulating epitranscriptomic
mechanisms and is closely linked to the normal functioning of diverse classes of RNAs, both …

Recent advances of pseudouridine (Ψ, 5-ribosyluracil) modification highlight its crucial role
as a post-transcriptional regulator in gene expression and its impact on various RNA …

Blood development and regeneration require rapid turnover of cells, and RNA modifications
play a key role in it via regulating stemness and cell fate regulation. RNA modifications effect …

RNA-guided pseudouridylation, a widespread post-transcriptional RNA modification, has
recently gained recognition for its role in cellular processes such as pre-mRNA splicing and …

Pseudouridine (Ψ) is among the most abundant RNA modification in the human
transcriptome and plays crucial roles in modulating mRNA stability, enhancing translation …