Hypoxic-ischemic encephalopathy (HIE) is an important cause of permanent damage to
central nervous system (CNS) that may result in neonatal death or manifest later as mental …

Stroke is a debilitating disease and has the ability to culminate in devastating clinical
outcomes. Ischemic stroke followed by reperfusion entrains cerebral ischemia/reperfusion …

Granulocyte colony stimulating factor (G-CSF) may enhance recovery from stroke through
neuroprotective mechanisms if administered early, or neurorepair if given later. Several …

Granulocyte colony-stimulating factor (G-CSF) is atherapeutic candidate for stroke that has
demonstrated anti-inflammatory and neuroprotective properties. Data from preclinical and …

Neural stem cells (NSCs) persist in the subventricular zone lining the ventricles of the adult
brain. The resident stem/progenitor cells can be stimulated in vivo by neurotrophic factors …

Background Granulocyte colony-stimulating factor (G-CSF) has shown neuroprotective and
neurogenerative activities in experimental studies, and our previous phase I clinical study …

Background Granulocyte colony-stimulating factor (G-CSF) has been shown to reduce
lesion volume and improve functional outcome in experimental stroke models. However …

Granulocyte colony-stimulating factor (G-CSF) is considered to be a novel neuroprotective
agent. Beneficial effects have been demonstrated by administrating G-CSF in different …

Background Granulocyte colony-stimulating factor (G-CSF; filgrastim) may be useful for the
treatment of acute ischemic stroke because of its neuroprotective and neurogenesis …

Background Drugs that promote angiogenesis include statins, recombinant human
granulocyte colony-stimulating factor, and stromal cell-derived factor-1. Low doses of …