Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …

Small-angle X-ray scattering (SAXS) is a biophysical method to study the overall shape and
structural transitions of biological macromolecules in solution. SAXS provides low resolution …

Quantitative studies in molecular and structural biology generally require accurate and
precise determination of protein concentrations, preferably via a method that is both quick …

Small-angle scattering of X-rays (SAXS) is an established method to study the overall
structure and structural transitions of biological macromolecules in solution. For folded …

Modern computational strategies have allowed for the direct modeling of the sedimentation
process of heterogeneous mixtures, resulting in sedimentation velocity (SV) size‐distribution …

Atomic-resolution structure determination is crucial for understanding protein function. Cryo-
EM and NMR spectroscopy both provide structural information, but currently cryo-EM does …

NMR spectroscopy is a key method for studying the structure and dynamics of (large)
multidomain proteins and complexes in solution. It plays a unique role in integrated …

Small-angle X-ray scattering (SAXS) is a robust technique for the comprehensive structural
characterizations of biological macromolecular complexes in solution. Here, we present a …

We have developed an approach for determining NMR structures of proteins over 20 kDa
that utilizes sparse distance restraints obtained using transverse relaxation optimized …

Atomic-level information about the structure and dynamics of biomolecules is critical for an
understanding of their function. Nuclear magnetic resonance (NMR) spectroscopy provides …