In vivo bio‐safety evaluations and diagnostic/therapeutic applications of chemically designed mesoporous silica nanoparticles
Y Chen, H Chen, J Shi - Advanced Materials, 2013 - Wiley Online Library
The remarkable progress of nanotechnology and its application in biomedicine have greatly
expanded the ranges and types of biomaterials from traditional organic material‐based …
expanded the ranges and types of biomaterials from traditional organic material‐based …
Emerging strategies of nanomaterial‐mediated tumor radiosensitization
Nano‐radiosensitization has been a hot concept for the past ten years, and the nanomaterial‐
mediated tumor radiosensitization method is mainly focused on increasing intracellular …
mediated tumor radiosensitization method is mainly focused on increasing intracellular …
[HTML][HTML] Metal-based nanoenhancers for future radiotherapy: radiosensitizing and synergistic effects on tumor cells
Y Liu, P Zhang, F Li, X **, J Li, W Chen, Q Li - Theranostics, 2018 - ncbi.nlm.nih.gov
Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past
decade, there has been growing interest in using high Z (atomic number) elements …
decade, there has been growing interest in using high Z (atomic number) elements …
[HTML][HTML] Nanoparticles for radiation therapy enhancement: the key parameters
This review focuses on the radiosensitization strategies that use high-Z nanoparticles. It
does not establish an exhaustive list of the works in this field but rather propose constructive …
does not establish an exhaustive list of the works in this field but rather propose constructive …
[HTML][HTML] Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer
Acquired radiation resistance is one of the major causes of radio therapy failure and
subsequent tumor relapse. Multiple approaches have been utilized to limit the radiation …
subsequent tumor relapse. Multiple approaches have been utilized to limit the radiation …
Engineered gadolinium-doped carbon dots for magnetic resonance imaging-guided radiotherapy of tumors
F Du, L Zhang, L Zhang, M Zhang, A Gong, Y Tan… - Biomaterials, 2017 - Elsevier
The effectiveness of radiotherapy can decrease due to inaccurate positioning of machinery
and inherent radioresistance of tumors. To address this issue, we present a novel …
and inherent radioresistance of tumors. To address this issue, we present a novel …
Engineered nanomaterial uptake and tissue distribution: from cell to organism
H Kettiger, A Schipanski, P Wick… - International journal of …, 2013 - Taylor & Francis
Improved understanding of interactions between nanoparticles and biological systems is
needed to develop safety standards and to design new generations of nanomaterials. This …
needed to develop safety standards and to design new generations of nanomaterials. This …
AGuIX nanoparticles enhance ionizing radiation-induced ferroptosis on tumor cells by targeting the NRF2-GPX4 signaling pathway
H Sun, H Cai, C Xu, H Zhai, F Lux, Y **e, L Feng… - Journal of …, 2022 - Springer
In the frame of radiotherapy treatment of cancer, radioresistance remains a major issue that
still needs solutions to be overcome. To effectively improve the radiosensitivity of tumors and …
still needs solutions to be overcome. To effectively improve the radiosensitivity of tumors and …
[HTML][HTML] Gadolinium-based nanoparticles and radiation therapy for multiple brain melanoma metastases: proof of concept before phase I trial
Nanoparticles containing high-Z elements are known to boost the efficacy of radiation
therapy. Gadolinium (Gd) is particularly attractive because this element is also a positive …
therapy. Gadolinium (Gd) is particularly attractive because this element is also a positive …
Long-Term in Vivo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection
We previously reported the synthesis of gadolinium-based nanoparticles (NPs) denoted
AGuIX (activation and guiding of irradiation by X-ray) NPs and demonstrated their potential …
AGuIX (activation and guiding of irradiation by X-ray) NPs and demonstrated their potential …