Role of JAK/STAT3 signaling in the regulation of metastasis, the transition of cancer stem cells, and chemoresistance of cancer by epithelial–mesenchymal transition
W ** - Cells, 2020 - mdpi.com
The JAK/STAT3 signaling pathway plays an essential role in various types of cancers.
Activation of this pathway leads to increased tumorigenic and metastatic ability, the transition …
Activation of this pathway leads to increased tumorigenic and metastatic ability, the transition …
Ca2+ fluxes and cancer
Ca 2+ ions are key second messengers in both excitable and non-excitable cells. Owing to
the rather pleiotropic nature of Ca 2+ transporters and other Ca 2+-binding proteins …
the rather pleiotropic nature of Ca 2+ transporters and other Ca 2+-binding proteins …
Akt-targeted therapy as a promising strategy to overcome drug resistance in breast cancer–A comprehensive review from chemotherapy to immunotherapy
Breast cancer is the most frequently occurring cancer in women. Chemotherapy in
combination with immunotherapy has been used to treat breast cancer. Atezolizumab …
combination with immunotherapy has been used to treat breast cancer. Atezolizumab …
[HTML][HTML] Calcium signaling and the therapeutic targeting of cancer cells
AHL Bong, GR Monteith - Biochimica et Biophysica Acta (BBA)-Molecular …, 2018 - Elsevier
The calcium signal is implicated in a variety of processes important in tumor progression (eg
proliferation and invasiveness). The calcium signal has also been shown to be important in …
proliferation and invasiveness). The calcium signal has also been shown to be important in …
Microcalcifications in breast cancer: From pathophysiology to diagnosis and prognosis
S O'Grady, MP Morgan - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2018 - Elsevier
The implementation of mammographic screening programmes in many countries has been
linked to a marked increase in early detection and improved prognosis for breast cancer …
linked to a marked increase in early detection and improved prognosis for breast cancer …
Calcium signaling in cancer progression and therapy
L Wu, W Lian, L Zhao - The FEBS journal, 2021 - Wiley Online Library
The old Greek aphorism 'Panta Rhei'('everything flows') is true for all living things in general.
As a dynamic process, calcium signaling plays fundamental roles in cellular activities under …
As a dynamic process, calcium signaling plays fundamental roles in cellular activities under …
Mechanosensitive ion channels push cancer progression
Z Pethő, K Najder, E Bulk, A Schwab - Cell Calcium, 2019 - Elsevier
In many cases, the mechanical properties of a tumor are different from those of the host
tissue. Mechanical cues regulate cancer development by affecting both tumor cells and their …
tissue. Mechanical cues regulate cancer development by affecting both tumor cells and their …
Red (635 nm), near-infrared (808 nm) and violet-blue (405 nm) photobiomodulation potentiality on human osteoblasts and mesenchymal stromal cells: a …
A Tani, F Chellini, M Giannelli, D Nosi… - International journal of …, 2018 - mdpi.com
Photobiomodulation (PBM) has been used for bone regenerative purposes in different fields
of medicine and dentistry, but contradictory results demand a skeptical look for its potential …
of medicine and dentistry, but contradictory results demand a skeptical look for its potential …
Ion channels in the regulation of autophagy
Autophagy is a cellular process in which the cell degrades and recycles its own constituents.
Given the crucial role of autophagy in physiology, deregulation of autophagic machinery is …
Given the crucial role of autophagy in physiology, deregulation of autophagic machinery is …
The role of TRPC1 in modulating cancer progression
Calcium ions (Ca2+) play an important role as second messengers in regulating a plethora
of physiological and pathological processes, including the progression of cancer. Several …
of physiological and pathological processes, including the progression of cancer. Several …