Insulin is a therapeutically relevant molecule with use in treating diabetes patients.
Unfortunately, it undergoes a range of untoward and often unpredictable physical …

Time-resolved small-and wide-angle X-ray scattering studies of proteins in solution based
on the pump-probe approach unveil structural information from intermediates over a broad …

Correlated motions of proteins are critical to function, but these features are difficult to
resolve using traditional structure determination techniques. Time-resolved X-ray methods …

Energy, structure, and charge are fundamental quantities characterizing a molecule.
Whereas the energy flow and structure change in chemical reactions are experimentally …

Association and dissociation of proteins are important biochemical events. In this Feature
Article, we analyze the available studies of these processes for insulin oligomers in aqueous …

The Trp-cage miniprotein is one of the smallest systems to exhibit a stable secondary
structure and fast-folding dynamics, serving as an apt model system to study transient …

Insulin is a principal hormone that is involved in the regulation of glucose levels in the blood.
Oral insulin formulation is a recent development in drug delivery systems. Biocompatible …

Infections caused by Staphylococcus aureus depend on its ability to acquire nutrients. One
essential nutrient is iron, which is obtained from the heme of the human host hemoglobin …

Protein dynamics are essential to biological function, and methods to determine such
structural rearrangements constitute a frontier in structural biology. Synchrotron radiation …

The structure of a protein is closely related to its biological function. In this regard, structural
changes, as well as static structures, have been scrutinized as essential elements in …