How electroconvulsive therapy works?: understanding the neurobiological mechanisms

A Singh, SK Kar - Clinical Psychopharmacology and …, 2017 - pmc.ncbi.nlm.nih.gov
Electroconvulsive therapy (ECT) is a time tested treatment modality for the management of
various psychiatric disorders. There have been a lot of modifications in the techniques of …

Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology

DT Balu, I Lucki - Neuroscience & Biobehavioral Reviews, 2009 - Elsevier
It is now well established that the mammalian brain has the capacity to produce new
neurons into adulthood. One such region that provides the proper milieu to sustain …

Prediction of individual response to electroconvulsive therapy via machine learning on structural magnetic resonance imaging data

R Redlich, N Opel, D Grotegerd, K Dohm… - JAMA …, 2016 - jamanetwork.com
Importance Electroconvulsive therapy (ECT) is one of the most effective treatments for
severe depression. However, biomarkers that accurately predict a response to ECT remain …

Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates

TD Perera, JD Coplan, SH Lisanby, CM Lipira… - Journal of …, 2007 - jneurosci.org
New neurons are generated in the adult hippocampus of many species including rodents,
monkeys, and humans. Conditions associated with major depression, such as social stress …

Volume increase in the dentate gyrus after electroconvulsive therapy in depressed patients as measured with 7T

JO Nuninga, RCW Mandl, MP Boks, S Bakker… - Molecular …, 2020 - nature.com
Electroconvulsive therapy (ECT) is the most effective treatment for depression, yet its
working mechanism remains unclear. In the animal analog of ECT, neurogenesis in the …

Angiogenesis is associated with blood–brain barrier permeability in temporal lobe epilepsy

V Rigau, M Morin, MC Rousset, F De Bock, A Lebrun… - Brain, 2007 - academic.oup.com
Previous studies from our group, focusing on neuro-glial remodelling in human temporal
lobe epilepsy (TLE), have shown the presence of immature vascular cells in various areas of …

[HTML][HTML] The neurobiological effects of electroconvulsive therapy studied through magnetic resonance: what have we learned, and where do we go?

OT Ousdal, GE Brancati, U Kessler, V Erchinger… - Biological …, 2022 - Elsevier
Electroconvulsive Therapy (ECT) is an established treatment choice for severe, treatment-
resistant depression, yet its mechanisms of action remain elusive. Magnetic resonance …

Molecular and cellular basis of epileptogenesis in symptomatic epilepsy

A Pitkänen, K Lukasiuk - Epilepsy & behavior, 2009 - Elsevier
Epileptogenesis refers to a process in which an initial brain-damaging insult triggers a
cascade of molecular and cellular changes that eventually lead to the occurrence of …

Chronic social stress inhibits cell proliferation in the adult medial prefrontal cortex: hemispheric asymmetry and reversal by fluoxetine treatment

B Czéh, JIH Müller-Keuker, R Rygula… - …, 2007 - nature.com
Profound neuroplastic changes have been demonstrated in various limbic structures after
chronic stress exposure and antidepressant treatment in animal models of mood disorders …

Chronic unpredictable stress decreases cell proliferation in the cerebral cortex of the adult rat

M Banasr, GW Valentine, XY Li, SL Gourley… - Biological …, 2007 - Elsevier
BACKGROUND: One of the most consistent morphologic findings in postmortem studies of
brain tissue from depressed patients is a decrease in the number of glia in the prefrontal …