In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

CD8+ cytotoxic T lymphocytes (CTLs) are preferred immune cells for targeting cancer.
During cancer progression, CTLs encounter dysfunction and exhaustion due to …

T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …

Macrophages are the most abundant cells within the tumor stroma displaying noticeable
plasticity, which allows them to perform several functions within the tumor microenvironment …

Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …

Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …

Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine
has gained a crucial role in cancer treatment. The advances in the field have led to the …

Recent discoveries in cancer metabolism have revealed promising metabolic targets to
modulate cancer progression, drug response, and anti-cancer immunity. Combination …