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Genetics of congenital heart disease: the glass half empty
AC Fahed, BD Gelb, JG Seidman… - Circulation research, 2013 - Am Heart Assoc
Congenital heart disease (CHD) is the most common congenital anomaly in newborn
babies. Cardiac malformations have been produced in multiple experimental animal …
babies. Cardiac malformations have been produced in multiple experimental animal …
The formation and function of the cardiac conduction system
JH van Weerd, VM Christoffels - Development, 2016 - journals.biologists.com
The cardiac conduction system (CCS) consists of distinctive components that initiate and
conduct the electrical impulse required for the coordinated contraction of the cardiac …
conduct the electrical impulse required for the coordinated contraction of the cardiac …
Signaling and transcriptional networks in heart development and regeneration
BG Bruneau - Cold Spring Harbor perspectives in …, 2013 - cshperspectives.cshlp.org
The mammalian heart is the first functional organ, the first indicator of life. Its normal
formation and function are essential for fetal life. Defects in heart formation lead to …
formation and function are essential for fetal life. Defects in heart formation lead to …
Genome-wide association study of PR interval
A Pfeufer, C Van Noord, KD Marciante, DE Arking… - Nature …, 2010 - nature.com
The electrocardiographic PR interval (or PQ interval) reflects atrial and atrioventricular nodal
conduction, disturbances of which increase risk of atrial fibrillation. We report a meta …
conduction, disturbances of which increase risk of atrial fibrillation. We report a meta …
Transcriptomic profiling of the develo** cardiac conduction system at single-cell resolution
Rationale: The cardiac conduction system (CCS) consists of distinct components including
the sinoatrial node, atrioventricular node, His bundle, bundle branches, and Purkinje fibers …
the sinoatrial node, atrioventricular node, His bundle, bundle branches, and Purkinje fibers …
Transcription factor pathways and congenital heart disease
DJ McCulley, BL Black - Current topics in developmental biology, 2012 - Elsevier
Congenital heart disease is a major cause of morbidity and mortality throughout life.
Mutations in numerous transcription factors have been identified in patients and families with …
Mutations in numerous transcription factors have been identified in patients and families with …