Immunological lessons from respiratory syncytial virus vaccine development
Respiratory syncytial virus (RSV) has eluded active vaccination efforts for more than five
decades and continues to cause substantial morbidity and mortality in infants, the …
decades and continues to cause substantial morbidity and mortality in infants, the …
Biology of infection and disease pathogenesis to guide RSV vaccine development
S Boyoglu-Barnum, T Chirkova… - Frontiers in …, 2019 - frontiersin.org
Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract disease
in young children and a substantial contributor to respiratory tract disease throughout life …
in young children and a substantial contributor to respiratory tract disease throughout life …
[HTML][HTML] Biomimetic metal-organic frameworks as protective scaffolds for live-virus encapsulation and vaccine stabilization
The invaluable health, economic and social impacts of vaccination are hard to exaggerate.
The ability to stabilize vaccines is urgently required for their equitable distribution without the …
The ability to stabilize vaccines is urgently required for their equitable distribution without the …
Mucosal administration of a live attenuated recombinant COVID-19 vaccine protects nonhuman primates from SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the COVID-19 global pandemic. SARS-CoV-2 is an enveloped RNA virus that relies on its …
the COVID-19 global pandemic. SARS-CoV-2 is an enveloped RNA virus that relies on its …
A contemporary view of respiratory syncytial virus (RSV) biology and strain-specific differences
MC Pandya, SM Callahan, KG Savchenko, CC Stobart - Pathogens, 2019 - mdpi.com
Respiratory syncytial virus (RSV) is a human respiratory pathogen which remains a leading
viral cause of hospitalizations and mortality among infants in their first year of life. Here, we …
viral cause of hospitalizations and mortality among infants in their first year of life. Here, we …
High thermostability improves neutralizing antibody responses induced by native-like HIV-1 envelope trimers
I del Moral-Sánchez, RA Russell, EE Schermer… - npj Vaccines, 2022 - nature.com
Soluble HIV-1 envelope glycoprotein (Env) immunogens are a prime constituent of
candidate vaccines designed to induce broadly neutralizing antibodies. Several lines of …
candidate vaccines designed to induce broadly neutralizing antibodies. Several lines of …
Respiratory syncytial virus infection: treatments and clinical management
Respiratory syncytial virus (RSV) is a major healthcare concern, especially for immune-
compromised individuals and infants below 5 years of age. Worldwide, it is known to be …
compromised individuals and infants below 5 years of age. Worldwide, it is known to be …
Mucosal application of a low-energy electron inactivated respiratory syncytial virus vaccine shows protective efficacy in an animal model
V Eberlein, M Ahrends, L Bayer, J Finkensieper… - Viruses, 2023 - mdpi.com
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract
infections in the elderly and in children, associated with pediatric hospitalizations. Recently …
infections in the elderly and in children, associated with pediatric hospitalizations. Recently …
Attenuation of human respiratory viruses by synonymous genome recoding
C Le Nouën, PL Collins, UJ Buchholz - Frontiers in Immunology, 2019 - frontiersin.org
Using computer algorithms and commercial DNA synthesis, one or more ORFs of a
microbial pathogen such as a virus can be recoded and deoptimized by several strategies …
microbial pathogen such as a virus can be recoded and deoptimized by several strategies …
An epitope-specific chemically defined nanoparticle vaccine for respiratory syncytial virus
A Zuniga, O Rassek, M Vrohlings, A Marrero-Nodarse… - NPJ vaccines, 2021 - nature.com
Respiratory syncytial virus (RSV) can cause severe respiratory disease in humans,
particularly in infants and the elderly. However, attempts to develop a safe and effective …
particularly in infants and the elderly. However, attempts to develop a safe and effective …