The most favored approach for drug administration is the oral route. Several anticancer
drugs come under this category and mostly lack solubility and oral bioavailability, which are …

Most recently discovered active pharmaceutical molecules and market-approved medicines
are poorly soluble in water, resulting in limited drug bioavailability and therapeutic …

Ibrutinib (IBR) is a biopharmaceutical classification system (BCS) class II drug and an
irreversible Bruton's tyrosine kinase (BTK) inhibitor. IBR has an extremely low oral …

Ritonavir has been reported in seven crystal forms notably form I, II, IIIb and IV, as well as a
hydrate, an L-tyrosine co-crystal and a formamide solvate. A new form is reported here with …

The present research work attempted to improve the oral bioavailability of the antiviral drug
Efavirenz (EFV) using a pharmaceutical cocrystallization technique. EFV comes under BCS …

Pharmaceutical cocrystals offer a versatile approach to enhancing the properties of drug
compounds, making them an important tool in drug formulation and development by …

Highlights•Solvent solution crystallization allows best control of material attributes of co-
crystals.•Crystal structures of co-crystals directly govern mechanical properties.•Tabletability …

Drug-drug cocrystals (DDCs) are a subclass of pharmaceutical cocrystals in which both the
components of a cocrystal are active drugs. DDCs are the recent advancement based on the …

The concept of Co-crystallization discovered almost a century ago, but it has inspired a great
interest of researchers in modern day due to their ability to improve physical properties of …

Alteration of solid form via a multicomponent crystal formation can be a choice to improve
the solubility of a poor solubility drug, such as dexibuprofen. The purpose of this research …