Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this
might lead to associations between alleles in the population—a property known as linkage …

▪ Abstract Molecular clocks have profoundly influenced modern views on the timing of
important events in evolutionary history. We review recent advances in estimating …

Detecting selective sweeps from genomic SNP data is complicated by the intricate
ascertainment schemes used to discover SNPs, and by the confounding influence of the …

The hitchhiking effect of a beneficial mutation, or a selective sweep, generates a unique
distribution of allele frequencies and spatial distribution of polymorphic sites. A composite …

In Drosophila and humans, there are accumulating examples of loci with a significant excess
of high-frequency-derived alleles or high levels of linkage disequilibrium, relative to a …

Accurately inferring the genome-wide landscape of recombination rates in natural
populations is a central aim in genomics, as patterns of linkage influence everything from …

The genomics revolution has spurred the undertaking of HapMap studies of numerous
species, allowing for population genomics to increase the understanding of how selection …

Studies of morphology, interspecific hybridization, protein/DNA sequences, and levels of
gene expression have suggested that sex-related characters (particularly those involved in …

One of the central goals of evolutionary biology is to understand the genetic basis of
adaptive evolution. The availability of nearly complete genome sequences from a variety of …

The rapidly expanding availability of large NGS data sets provides an opportunity to
investigate population genetics at an unprecedented scale. Drosophila simulans is the sister …