Microfluidics-based sensing of biospecies

Y **ng, L Zhao, Z Cheng, C Lv, F Yu… - ACS Applied Bio …, 2020 - ACS Publications
Over the past decades, microfluidic devices based on many advanced techniques have
aroused widespread attention in the fields of chemical, biological, and analytical …

Glass capillary-based nanopores for single molecule/single cell detection

X Guan, H Li, L Chen, G Qi, Y ** - ACS sensors, 2023 - ACS Publications
A glass capillary-based nanopore (G-nanopore), due to its tapered tip, easy tunability in
orifice size, and especially its flexible surface modifications that can be tailored to effectively …

Electrochemical sensing at a confined space

SM Lu, YY Peng, YL Ying, YT Long - Analytical chemistry, 2020 - ACS Publications
Single entity sensing is recently an area of tremendous interest in analytical chemistry, such
that it is possible to analyze single cells, single particles, and even single molecules. Among …

Real-time monitoring of exosomes secretion from single cell using dual-nanopore biosensors

H Zhang, X Zheng, T Zhao, Y Chen, Y Luo, Y Dong… - ACS …, 2023 - ACS Publications
Exosomes secreted from cells carry rich information from their parent cells, representing a
promising biomarker for investigation of diseases. We develop a dual-nanopore biosensor …

Nanoconfinement effect for signal amplification in electrochemical analysis and sensing

J Zhang, L Zhang, Z Li, Q Zhang, Y Li, Y Ying, Y Fu - Small, 2021 - Wiley Online Library
Owing to the urgent need for electrochemical analysis and sensing of trace target molecules
in various fields such as medical diagnosis, agriculture and food safety, and environmental …

Ion current rectification-nanopipette technique for single-cell analysis

YT Xu, YF Ruan, TY Zhang, XM Shi, HY Wang… - TrAC Trends in …, 2023 - Elsevier
Single-cell analysis (SCA) could provide in-depth understanding of cell biology yet is of
great challenge. Many attempts have been made to develop novel techniques for SCA …

A practical electrochemical nanotool for facile quantification of amino acids in single cell

YT Xu, YF Ruan, HY Wang, SY Yu, XD Yu, WW Zhao… - Small, 2021 - Wiley Online Library
Though significant advances are made in the arena of single‐cell electroanalysis,
quantification of intracellular amino acids of human cells remains unsolved. Exemplified by l …

Selective sensing of proteins using aptamer functionalized nanopore extended field‐effect transistors

R Ren, X Wang, S Cai, Y Zhang, Y Korchev… - Small …, 2020 - Wiley Online Library
The ability to sense proteins and protein‐related interactions at the single‐molecule level is
becoming of increasing importance to understand biological processes and diseases better …

Nanopipettes for single nanobubble electrochemical analysis: Fundamentals and applications

H Zhou, K Chen, RJ Yu, YL Ying, Q Chen… - Current Opinion in …, 2023 - Elsevier
Gas bubbles have attracted increasing attention due to their significant roles in various
electrochemical processes. It is crucial to understand their generation, dynamic evolution …

Stimuli-responsive polymers for interface engineering toward enhanced electrochemical analysis of neurochemicals

S Ding, G Shi, A Zhu - Chemical Communications, 2022 - pubs.rsc.org
Neurochemical monitoring can provide important insights into the chemical communications
in the brain and neurological diseases. Although electrochemical sensors have promoted …