Clinical measures of bulbar dysfunction in ALS

Y Yunusova, EK Plowman, JR Green, C Barnett… - Frontiers in …, 2019 - frontiersin.org
Bulbar impairment represents a hallmark feature of Amyotrophic Lateral Sclerosis (ALS) that
significantly impacts survival and quality of life. Speech and swallowing dysfunction are key …

Machine learning in amyotrophic lateral sclerosis: achievements, pitfalls, and future directions

V Grollemund, PF Pradat, G Querin, F Delbot… - Frontiers in …, 2019 - frontiersin.org
Background: Amyotrophic Lateral Sclerosis (ALS) is a relentlessly progressive
neurodegenerative condition with limited therapeutic options at present. Survival from …

[PDF][PDF] Automatic Speech Recognition of Disordered Speech: Personalized Models Outperforming Human Listeners on Short Phrases.

JR Green, RL MacDonald, PP Jiang, J Cattiau… - Interspeech, 2021 - researchgate.net
This study evaluated the accuracy of personalized automatic speech recognition (ASR) for
recognizing disordered speech from a large cohort of individuals with a wide range of …

“You say severe, I say mild”: Toward an empirical classification of dysarthria severity

KL Stipancic, KM Palmer, HP Rowe… - Journal of Speech …, 2021 - pubs.asha.org
Purpose: The main purpose of this study was to create an empirical classification system for
speech severity in patients with dysarthria secondary to amyotrophic lateral sclerosis (ALS) …

Characterizing dysarthria diversity for automatic speech recognition: A tutorial from the clinical perspective

HP Rowe, SE Gutz, MF Maffei, K Tomanek… - Frontiers in computer …, 2022 - frontiersin.org
Despite significant advancements in automatic speech recognition (ASR) technology, even
the best performing ASR systems are inadequate for speakers with impaired speech. This …

A new dataset for facial motion analysis in individuals with neurological disorders

A Bandini, S Rezaei, DL Guarín… - IEEE Journal of …, 2020 - ieeexplore.ieee.org
We present the first public dataset with videos of oro-facial gestures performed by
individuals with oro-facial impairment due to neurological disorders, such as amyotrophic …

Speech movement measures as markers of bulbar disease in amyotrophic lateral sclerosis

S Shellikeri, JR Green, M Kulkarni, P Rong… - Journal of Speech …, 2016 - pubs.asha.org
Purpose The goal of this study was to identify the effects of amyotrophic lateral sclerosis
(ALS) on tongue and jaw control, both cross-sectionally and longitudinally. The data were …

Rate of speech decline in individuals with amyotrophic lateral sclerosis

M Eshghi, Y Yunusova, KP Connaghan, BJ Perry… - Scientific Reports, 2022 - nature.com
Although speech declines rapidly in some individuals with amyotrophic lateral sclerosis
(ALS), longitudinal changes in speech have rarely been characterized. The study objectives …

Predicting speech intelligibility decline in amyotrophic lateral sclerosis based on the deterioration of individual speech subsystems

P Rong, Y Yunusova, J Wang, L Zinman, GL Pattee… - PloS one, 2016 - journals.plos.org
Purpose To determine the mechanisms of speech intelligibility impairment due to neurologic
impairments, intelligibility decline was modeled as a function of co-occurring changes in the …