Rodents are widely used to mimic human diseases to improve understanding of the causes
and progression of disease symptoms and to test potential therapeutic interventions …

Diet is a critical element determining human health and diseases, and unbalanced food
habits are major risk factors for the development of obesity and related metabolic disorders …

Aim We sought develop and characterize a diet-induced model of metabolic syndrome and
its related diseases. Methods The experimental animals (Spague-Dawley rats) were …

The study examines the influence of three types of hypercaloric diets on metabolic
parameters, inflammatory markers, and oxidative stress in experimental model. Male Wistar …

Background It has been proposed that the γ-aminobutyric acid (GABA) plays a key role in
the regulation of food intake and body weight by controlling the excitability, plasticity and the …

The attenuation of oxidative stress could be an important mechanism whereby the incidence
of vascular complications in the MS (metabolic syndrome) may be diminished. The present …

Obesity is a disease that has become a serious public health issue worldwide, and chronic
stressors, which are a problem for modern society, cause neuroendocrine changes with …

New Findings What is the topic of this review? The Zucker Diabetic‐Sprague Dawley
(ZDSD) rat is in the early adoption phase of use by researchers in the fields of diabetes …

This study examined whether sucrose, fructose, aspartame, and saccharin influences the
association between obesity and glucose tolerance in 2856 adults from the NHANES III …

Obesity is one of the major risk factors for cardiovascular diseases and its prevalence is
increasing in all age groups, with the biggest impact observed in middle-aged and older …