Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Causes, consequences, and treatment of metabolically unhealthy fat distribution

N Stefan - The lancet Diabetes & endocrinology, 2020 - thelancet.com
An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

GH Goossens, JWE Jocken, EE Blaak - Nature Reviews Endocrinology, 2021 - nature.com
Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

Diabetes as a risk factor for stroke in women compared with men: a systematic review and meta-analysis of 64 cohorts, including 775 385 individuals and 12 539 …

SAE Peters, RR Huxley, M Woodward - The Lancet, 2014 - thelancet.com
Background Diabetes mellitus is a major cause of death and disability worldwide and is a
strong risk factor for stroke. Whether and to what extent the excess risk of stroke conferred by …

Sex differences in cardiovascular risk factors and disease prevention

Y Appelman, BB van Rijn, ME Ten Haaf, E Boersma… - Atherosclerosis, 2015 - Elsevier
Cardiovascular disease (CVD) has been seen as a men's disease for decades, however it is
more common in women than in men. It is generally assumed in medicine that the effects of …

Diabetes as risk factor for incident coronary heart disease in women compared with men: a systematic review and meta-analysis of 64 cohorts including 858,507 …

SAE Peters, RR Huxley, M Woodward - Diabetologia, 2014 - Springer
Aims/hypothesis A previous pooled analysis suggested that women with diabetes are at
substantially increased risk of fatal CHD compared with affected men. Additional findings …

Gender differences in insulin resistance, body composition, and energy balance

EB Geer, W Shen - Gender medicine, 2009 - Elsevier
Background: Men and women differ substantially in regard to degrees of insulin resistance,
body composition, and energy balance. Adipose tissue distribution, in particular the …

The role of adipokines in chronic inflammation

P Mancuso - ImmunoTargets and therapy, 2016 - Taylor & Francis
Adipose tissue has traditionally been defined as connective tissue that stores excess
calories in the form of triacylglycerol. However, the physiologic functions attributed to …

Testosterone and obesity

DM Kelly, TH Jones - Obesity Reviews, 2015 - Wiley Online Library
Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …

[HTML][HTML] Testosterone: a metabolic hormone in health and disease

DM Kelly, TH Jones - Journal of Endocrinology, 2013 - joe.bioscientifica.com
Testosterone is a hormone that plays a key role in carbohydrate, fat and protein metabolism.
It has been known for some time that testosterone has a major influence on body fat …