Targeting MYH9 represses USP14-mediated NAP1L1 deubiquitination and cell proliferation in glioma

Z Chen, X Yan, C Miao, L Liu, S Liu, Y **a… - Cancer Cell …, 2023 - Springer
Abstract Myosin heavy chain 9 (MYH9) plays an important role in a number of diseases.
Nevertheless, the function of MYH9 in glioma is unclear. The present research aimed to …

Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation

T Li, Z Niu, T Yu, J Li, X Lu, M Huang, Q Wang… - MedComm, 2023 - Wiley Online Library
Myocardial fibrosis post myocardial infarction (MI) is characterized by abnormal extracellular
matrix (ECM) deposition and cardiac dysfunction could finally develop into serious heart …

[HTML][HTML] NAP1L1 targeting suppresses the proliferation of nasopharyngeal carcinoma

YH Liu, XN Li, YW Zhang, Y Tang, WY Fang… - Biomedicine & …, 2021 - Elsevier
Abstract Nucleosome assembly protein 1-like 1 (NAP1L1) is significantly involved in the
development of various cancers. However, its role in the molecular mechanism of …

NAP1L1 functions as a novel prognostic biomarker associated with macrophages and promotes tumor progression by influencing the Wnt/β-catenin pathway in …

B Shen, W Zhu, X Liu, J Jiang - Frontiers in Genetics, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is regarded as one of the universal cancers in the world.
Therefore, our study is based on clinical, molecular mechanism and immunological …

NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth

S Liu, Y Zhang, S Cui, D Song, B Li, Q Chen… - Cancer Cell …, 2021 - Springer
Background Breast cancer is a common cancer among women in the world. However, its
pathogenesis is still to be determined. The role and molecular mechanism of Nucleosome …

DEAD-box helicase 27 triggers epithelial to mesenchymal transition by regulating alternative splicing of lipoma-preferred partner in gastric cancer metastasis

Y **, S Yang, X Gao, D Chen, T Luo, S Su, Y Shi… - Frontiers in …, 2022 - frontiersin.org
DEAD-box helicase 27 (DDX27) was previously identified as an important mediator during
carcinogenesis, while its role in gastric cancer (GC) is not yet fully elucidated. Here, we …

[HTML][HTML] Proteomic profiling of oleamide-mediated polarization in a primary human monocyte-derived tumor-associated macrophages (TAMs) model: a functional …

P Wisitpongpun, W Buakaew, S Pongcharoen… - PeerJ, 2024 - peerj.com
Background Tumor-associated macrophages (TAMs) play a critical function in the
development of tumors and are associated with protumor M2 phenotypes. Shifting TAMs …

Nucleosome assembly protein 1-like 1 (NAP1L1) in gastric cancer patients: A potential biomarker with diagnostic and prognostic utility

G Gul, MA Aydin, S Algul, R Kiziltan, O Kemik - Biomarkers, 2024 - Taylor & Francis
Background The nucleosome assembly protein 1-like 1 (NAP1L1) is suggested to have an
oncogenic role in several tumors based on its overexpression. However, its diagnostic and …

NAP1L1 is a novel microtubule‐associated protein

N Peng, Y Zhang, X Zhang, HY Wu… - Cytoskeleton, 2023 - Wiley Online Library
Microtubule‐associated proteins (MAPs) regulate assembly and stability of microtubules
(MTs) during cell cytokinesis, cell migration, neuronal growth, axon guidance, and synapse …

[HTML][HTML] Systemic immune profiling analysis identifying M2-TAM related genes predicted colon cancer prognosis and chemotherapy responses

X Liu, D Liu, J Wang - Medicine, 2024 - journals.lww.com
Colon cancer (COAD) poses great challenges to clinical treatment due to its heterogeneity
and complex immune microenvironment. M2-like macrophages significantly influence …