Biomarkers, oxidative stress and autophagy in skin aging

Y Gu, J Han, C Jiang, Y Zhang - Ageing research reviews, 2020 - Elsevier
Aging is a major cause of many degenerative diseases. The most intuitive consequence of
aging is mainly manifested on the skin, resulting in cumulative changes in skin structure …

Food anthocyanins: Malvidin and its glycosides as promising antioxidant and anti-inflammatory agents with potential health benefits

A Merecz-Sadowska, P Sitarek, T Kowalczyk, K Zajdel… - Nutrients, 2023 - mdpi.com
Anthocyanins are flavonoid compounds that are abundantly present in fruits and vegetables.
These compounds contribute to the color of these foods and offer various health benefits to …

Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci

CB Stein, AR Field, CA Mimoso, CC Zhao, KL Huang… - Molecular cell, 2022 - cell.com
Summary RNA polymerase II (RNAPII) pausing in early elongation is critical for gene
regulation. Paused RNAPII can be released into productive elongation by the kinase P-TEFb …

High-throughput identification of repurposable neuroactive drugs with potent anti-glioblastoma activity

S Lee, T Weiss, M Bühler, J Mena, Z Lottenbach… - Nature Medicine, 2024 - nature.com
Glioblastoma, the most aggressive primary brain cancer, has a dismal prognosis, yet
systemic treatment is limited to DNA-alkylating chemotherapies. New therapeutic strategies …

SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells

T Patra, K Meyer, L Geerling, TS Isbell, DF Hoft… - PLoS …, 2020 - journals.plos.org
Cytokine storm is suggested as one of the major pathological characteristics of SARS-CoV-2
infection, although the mechanism for initiation of a hyper-inflammatory response, and multi …

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

EB Kurutas - Nutrition journal, 2015 - Springer
Remarkable interest has risen in the idea that oxidative/nitrosative stress is mediated in the
etiology of numerous human diseases. Oxidative/Nitrosative stress is the result of an …

The role of reactive oxygen species in arsenic toxicity

Y Hu, J Li, B Lou, R Wu, G Wang, C Lu, H Wang, J Pi… - Biomolecules, 2020 - mdpi.com
Arsenic poisoning is a global health problem. Chronic exposure to arsenic has been
associated with the development of a wide range of diseases and health problems in …

[HTML][HTML] Antioxidant responses and cellular adjustments to oxidative stress

C Espinosa-Diez, V Miguel, D Mennerich, T Kietzmann… - Redox biology, 2015 - Elsevier
Redox biological reactions are now accepted to bear the Janus faceted feature of promoting
both physiological signaling responses and pathophysiological cues. Endogenous …

Oxidation events and skin aging

A Kammeyer, RM Luiten - Ageing research reviews, 2015 - Elsevier
The rate of skin aging, or that of tissue in general, is determined by a variable predominance
of tissue degeneration over tissue regeneration. This review discusses the role of oxidative …

The hallmarks of flavonoids in cancer

LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …