Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

G-Quadruplexes attract growing interest as functional constituents in biology, chemistry,
nanotechnology, and material science. In particular, the reversible dynamic reconfiguration …

Artificial nucleic acid circuits with precisely controllable dynamic and function have shown
great promise in biosensing, but their utility in molecular diagnostics is still restrained by the …

Precise and sensitive analysis of exosomal microRNA (miRNA) is of great importance for
noninvasive early disease diagnosis, but it remains a great challenge to detect exosomal …

Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

DNA‐based machines have attracted rapidly growing interest owing to their potential in drug
delivery, biocomputing, and diagnostic applications. Herein, we report a type of exonuclease …

Nucleic acid cleavage processes contribute to target and signal amplification, which is
critical for the development of highly sensitive assays. 1, 2 Exonucleases or endonucleases …

DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …