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Management of psoriasis as a systemic disease: what is the evidence?
Background Psoriasis is a chronic, systemic immune‐mediated disease characterized by
development of erythematous, indurated, scaly, pruritic and often painful skin plaques …
development of erythematous, indurated, scaly, pruritic and often painful skin plaques …
Dyslipidemia in rheumatoid arthritis: the possible mechanisms
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease, of which the leading
cause of death is cardiovascular disease (CVD). The levels of total cholesterol (TC), low …
cause of death is cardiovascular disease (CVD). The levels of total cholesterol (TC), low …
Anti-inflammatory therapies for cardiovascular disease
Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …
the arterial wall. Rather, the initiation and progression of atherosclerotic lesions is currently …
Lipid metabolism and rheumatoid arthritis
As a chronic progressive autoimmune disease, rheumatoid arthritis (RA) is characterized by
mainly damaging the synovium of peripheral joints and causing joint destruction and early …
mainly damaging the synovium of peripheral joints and causing joint destruction and early …
EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis
MJL Peters, DPM Symmons, D McCarey… - Annals of the rheumatic …, 2010 - Elsevier
Objectives: To develop evidence-based EULAR recommendations for cardiovascular (CV)
risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and …
risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and …
[HTML][HTML] The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk
The recent insight that inflammation contributes to the development of atherosclerosis and
type 2 diabetes mellitus constitutes a major breakthrough in understanding the mechanisms …
type 2 diabetes mellitus constitutes a major breakthrough in understanding the mechanisms …
Role of TNF-α in vascular dysfunction
Healthy vascular function is primarily regulated by several factors including EDRF
(endothelium-dependent relaxing factor), EDCF (endothelium-dependent contracting factor) …
(endothelium-dependent relaxing factor), EDCF (endothelium-dependent contracting factor) …
Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
Pathogenesis of chronic plaque psoriasis and its intersection with cardio-metabolic comorbidities
Psoriasis is a chronic, systemic immune-mediated disease characterized by development of
erythematous, indurated, scaly, pruritic plaques on the skin. Psoriasis is frequently …
erythematous, indurated, scaly, pruritic plaques on the skin. Psoriasis is frequently …
Double‐blind randomized controlled clinical trial of the interleukin‐6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an …
RN Maini, PC Taylor, J Szechinski… - Arthritis & …, 2006 - Wiley Online Library
Objective To establish the safety and efficacy of repeat infusions of tocilizumab (previously
known as MRA), a humanized anti–interleukin‐6 (IL‐6) receptor antibody, alone and in …
known as MRA), a humanized anti–interleukin‐6 (IL‐6) receptor antibody, alone and in …