While blood-based tests are readily available for various conditions, including
cardiovascular diseases, type 2 diabetes, and common cancers, Alzheimer's disease (AD) …

Sepsis is the most common cause of admission to intensive care units worldwide. Sepsis
patients frequently suffer from sepsis-associated encephalopathy (SAE) reflecting acute …

Background and Objectives Studies associate chronic kidney disease (CKD) with
neurodegeneration. This study investigated the relationship between kidney function, blood …

Background Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that poses
a worldwide public health challenge. A neuroimaging biomarker would significantly improve …

Dementia is a chronic progressive cognitive decline illness that results in functional
impairment. Vascular dementia (VaD), second only to Alzheimer's disease (AD), is one of …

Objective To investigate the relationship between cortico-motor excitability and cognitive
reserve (CR) in cognitively unimpaired older adults (CU) and in older adults with mild …

Background Peripheral glial fibrillary acidic protein (GFAP) and neurofilament light chain
(NfL) are sensitive markers of neuroinflammation and neuronal damage. Previous studies …

We investigated the associations of plasma neurofilament light (NfL), glial fibrillary acidic
protein (GFAP), and total tau (t-tau) with markers of cerebral small vessel disease (SVD) and …

Background and purpose We aimed to evaluate the accuracy of plasma neurofilament light
chain (NfL) in predicting Alzheimer's disease (AD) and the progression of cognitive decline …

Background The accumulation of amyloid-β (Aβ) peptide in the brain is a hallmark of
Alzheimer's disease (AD), occurring years before symptom onset. Current methods for …