Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …

Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …

Natural products with antibacterial activity are highly desired globally to combat against
multidrug-resistant (MDR) bacteria. Antibacterial peptide (ABP), especially cyclic ABP …

The study of peptide-lipid and peptide-peptide interactions as well as their topology and
dynamics using biophysical and structural approaches have changed our view how …

Reprogramming biosynthetic assembly-lines is a topic of intense interest. This is
unsurprising as the scaffolds of most antibiotics in current clinical use are produced by such …

Many naturally occurring small peptides have significant therapeutic properties. Total
synthesis of these peptides is not only helpful in the identification of their structures and …

Throughout the ages the world has witnessed the outbreak of many infectious diseases.
Emerging microbial diseases pose a serious threat to public health. Increasing resistance of …

Tuberculosis (TB), an airborne infectious disease caused by Mycobacterium tuberculosis,
has become the leading cause of death. The subsequent emergence of multidrug-resistant …

Wollamides are cyclic hexapeptides, recently isolated from an Australian soil Streptomyces
isolate, that exhibit promising in vitro antimycobacterial activity against Mycobacterium bovis …

Macrocyclic peptides are privileged scaffolds for drug development and constitute a
significant portion of macrocyclic drugs on the market today in fields spanning from …