Insomnia disorder: State of the science and challenges for the future

D Riemann, F Benz, RJ Dressle… - Journal of sleep …, 2022‏ - Wiley Online Library
Insomnia disorder comprises symptoms during night and day that strongly affect quality of
life and wellbeing. Prolonged sleep latency, difficulties to maintain sleep and early morning …

[HTML][HTML] Brain mechanisms of insomnia: new perspectives on causes and consequences

EJW Van Someren - Physiological reviews, 2021‏ - journals.physiology.org
While insomnia is the second most common mental disorder, progress in our understanding
of underlying neurobiological mechanisms has been limited. The present review addresses …

Hyperarousal in insomnia disorder: Current evidence and potential mechanisms

RJ Dressle, D Riemann - Journal of Sleep Research, 2023‏ - Wiley Online Library
Insomnia disorder is among the most frequent mental disorders, making research on its
aetiology and pathophysiology particularly important. A unifying element of many …

Insomnia—A risk factor for mental disorders

E Hertenstein, F Benz, CL Schneider… - Journal of sleep …, 2023‏ - Wiley Online Library
Longitudinal studies observed that individuals suffering from insomnia disorder have a
higher vulnerability to develop symptoms of psychopathology compared with good sleepers …

Overnight neuronal plasticity and adaptation to emotional distress

Y Cabrera, KJ Koymans, GR Poe, HW Kessels… - Nature Reviews …, 2024‏ - nature.com
Expressions such as 'sleep on it'refer to the resolution of distressing experiences across a
night of sound sleep. Sleep is an active state during which the brain reorganizes the …

The emotional component of insomnia disorder: A focus on emotion regulation and affect dynamics in relation to sleep quality and insomnia

D Meneo, F Samea, M Tahmasian… - Journal of sleep …, 2023‏ - Wiley Online Library
Theoretical models of insomnia disorder recognise an emotional component in the
maintenance of the disorder. Nonetheless, the field of emotions is vast and different …

Restless REM sleep impedes overnight amygdala adaptation

R Wassing, O Lakbila-Kamal, JR Ramautar, D Stoffers… - Current Biology, 2019‏ - cell.com
Animal studies show that insufficient silencing of the locus coeruleus (LC) during REM sleep
impairs sleep-related brain plasticity. Restless REM sleep, a characteristic of several …

Chronic insomnia, REM sleep instability and emotional dysregulation: A pathway to anxiety and depression?

D Riemann, RJ Dressle, F Benz… - Journal of sleep …, 2024‏ - Wiley Online Library
The world‐wide prevalence of insomnia disorder reaches up to 10% of the adult population.
Women are more often afflicted than men, and insomnia disorder is a risk factor for somatic …

[HTML][HTML] Sleep disturbances in bereavement: A systematic review

M Lancel, M Stroebe, MC Eisma - Sleep medicine reviews, 2020‏ - Elsevier
Severe, persistent and disabling grief occurs among a sizable minority experiencing
bereavement, with diagnostic manuals newly including complicated grief (CG) disorders …

On the relationship between EEG spectral analysis and pre‐sleep cognitive arousal in insomnia disorder: Towards an integrated model of cognitive and cortical …

RJ Dressle, D Riemann, K Spiegelhalder… - Journal of Sleep …, 2023‏ - Wiley Online Library
According to the hyperarousal model, insomnia is characterised by increased arousal in the
cortical, cognitive, and physiological domains. However, the interaction between these …