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Advances in COVID-19 mRNA vaccine development
E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
Drug delivery systems for RNA therapeutics
RNA-based gene therapy requires therapeutic RNA to function inside target cells without
eliciting unwanted immune responses. RNA can be ferried into cells using non-viral drug …
eliciting unwanted immune responses. RNA can be ferried into cells using non-viral drug …
Evaluation of waning of SARS-CoV-2 vaccine–induced immunity: a systematic review and meta-analysis
Importance Estimates of the rate of waning of vaccine effectiveness (VE) against COVID-19
are key to assess population levels of protection and future needs for booster doses to face …
are key to assess population levels of protection and future needs for booster doses to face …
Class switch toward noninflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination
P Irrgang, J Gerling, K Kocher, D Lapuente… - Science …, 2022 - science.org
RNA vaccines are efficient preventive measures to combat the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic. High levels of neutralizing SARS-CoV-2 …
syndrome coronavirus 2 (SARS-CoV-2) pandemic. High levels of neutralizing SARS-CoV-2 …
New‐onset autoimmune phenomena post‐COVID‐19 vaccination
Y Chen, Z Xu, P Wang, XM Li, ZW Shuai, DQ Ye… - …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has led to an unprecedented setback for …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has led to an unprecedented setback for …
[HTML][HTML] Real-world effectiveness of COVID-19 vaccines: a literature review and meta-analysis
Objective To estimate the coronavirus disease 2019 (COVID-19) vaccine effectiveness (VE)
against concerned outcomes in real-world settings. Methods Studies reporting COVID-19 VE …
against concerned outcomes in real-world settings. Methods Studies reporting COVID-19 VE …
[HTML][HTML] Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study
Background Many countries are experiencing a resurgence of COVID-19, driven
predominantly by the delta (B. 1.617. 2) variant of SARS-CoV-2. In response, these countries …
predominantly by the delta (B. 1.617. 2) variant of SARS-CoV-2. In response, these countries …
Association between mRNA vaccination and COVID-19 hospitalization and disease severity
Importance A comprehensive understanding of the benefits of COVID-19 vaccination
requires consideration of disease attenuation, determined as whether people who develop …
requires consideration of disease attenuation, determined as whether people who develop …
[HTML][HTML] Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study
Background Vaccine effectiveness studies have not differentiated the effect of the delta (B.
1.617. 2) variant and potential waning immunity in observed reductions in effectiveness …
1.617. 2) variant and potential waning immunity in observed reductions in effectiveness …
Protection by a Fourth Dose of BNT162b2 against Omicron in Israel
Abstract Background On January 2, 2022, Israel began administering a fourth dose of
BNT162b2 vaccine to persons 60 years of age or older. Data are needed regarding the …
BNT162b2 vaccine to persons 60 years of age or older. Data are needed regarding the …