Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

BACKGROUND: Medical procedures often evoke pain and anxiety in pediatric patients.
Virtual reality (VR) is a relatively new intervention that can be used to provide distraction …

'How Emotions Are Made did what all great books do. It took a subject I thought I understood
and turned my understanding upside down'–Malcolm Gladwell, author of The Tip** Point …

BACKGROUND Primary dysmenorrhea, or painful menstruation in the absence of pelvic
pathology, is a common, and often debilitating, gynecological condition that affects between …

Sustained pain is a major characteristic of clinical pain disorders, but it is difficult to assess in
isolation from co-occurring cognitive and emotional features in patients. In this study, we …

The anterior cingulate cortex (ACC) is activated in both acute and chronic pain. In this
Review, we discuss increasing evidence from rodent studies that ACC activation contributes …

Objectives: This review aims to provide a framework for evaluating the utility of virtual reality
(VR) as a distraction intervention to alleviate pain and distress during medical procedures …

Pain and anxiety comorbidities are a common health problem, but the neural mechanisms
underlying comorbidity remain unclear. We propose that comorbidity implies that similar …

Background: Vaccine injections are the most common painful needle procedure
experienced throughout the lifespan. Many strategies are available to mitigate this pain; …

Cognitive impairment is commonly associated with the pain experience. This impairment
represents a major obstacle to daily activities and rehabilitation, especially in the chronic …