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[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …
Mycobacterium tuberculosis: success through dormancy
Tuberculosis (TB) remains a major health threat, killing nearly 2 million individuals around
this globe, annually. The only vaccine, developed almost a century ago, provides limited …
this globe, annually. The only vaccine, developed almost a century ago, provides limited …
The Mycobacterium tuberculosis regulatory network and hypoxia
We have taken the first steps towards a complete reconstruction of the Mycobacterium
tuberculosis regulatory network based on ChIP-Seq and combined this reconstruction with …
tuberculosis regulatory network based on ChIP-Seq and combined this reconstruction with …
Genomic insights into tuberculosis
Prevalent since pre-history, human tuberculosis—caused by the pathogen Mycobacterium
tuberculosis—remains a major source of death worldwide. Moreover, increasing drug …
tuberculosis—remains a major source of death worldwide. Moreover, increasing drug …
Letting Slee** dos Lie: Does Dormancy Play a Role in Tuberculosis?
MC Chao, EJ Rubin - Annual review of microbiology, 2010 - annualreviews.org
Mycobacterium tuberculosis, which causes tuberculosis, remains a major human public
health threat. This is largely due to a sizeable reservoir of latently infected individuals, who …
health threat. This is largely due to a sizeable reservoir of latently infected individuals, who …
Human Granuloma In Vitro Model, for TB Dormancy and Resuscitation
Tuberculosis (TB) is responsible for death of nearly two million people in the world annually.
Upon infection, Mycobacterium tuberculosis (Mtb) causes formation of granuloma where the …
Upon infection, Mycobacterium tuberculosis (Mtb) causes formation of granuloma where the …
Targeting Phenotypically Tolerant Mycobacterium tuberculosis
Two parallel revolutions were born in the golden era of antibiotics (~ 1940 to 1960). One
was a revolution in medicine as physicians went to war with microbes. The second was a …
was a revolution in medicine as physicians went to war with microbes. The second was a …
Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific
Foam cells are lipid-laden macrophages that contribute to the inflammation and tissue
damage associated with many chronic inflammatory disorders. Although foam cell …
damage associated with many chronic inflammatory disorders. Although foam cell …
An obligately aerobic soil bacterium activates fermentative hydrogen production to survive reductive stress during hypoxia
Oxygen availability is a major factor and evolutionary force determining the metabolic
strategy of bacteria colonizing an environmental niche. In the soil, conditions can switch …
strategy of bacteria colonizing an environmental niche. In the soil, conditions can switch …
Oxidative phosphorylation as a target space for tuberculosis: success, caution, and future directions
The genus Mycobacterium comprises a group of obligately aerobic bacteria that have
adapted to inhabit a wide range of intracellular and extracellular environments …
adapted to inhabit a wide range of intracellular and extracellular environments …