[HTML][HTML] Directly compressed rosuvastatin calcium tablets that offer hydrotropic and micellar solubilization for improved dissolution rate and extent of drug release
The objective was to use caffeine and Soluplus® to improve the dissolution rate and to
maintain a concentration of BCS Class II rosuvastatin calcium that exceeds its solubility …
maintain a concentration of BCS Class II rosuvastatin calcium that exceeds its solubility …
Production of rosuvastatin calcium nanoparticles using gas antisolvent technique: Experimental and optimization
The activity of pharmaceutical substances crucially depends on the bioavailability of the
substances. The bioavailability of drugs in body and their rate of dissolution in the biological …
substances. The bioavailability of drugs in body and their rate of dissolution in the biological …
Solubility and thermodynamics of apremilast in different mono solvents: Determination, correlation and molecular interactions
The solubility data of recently launched poorly soluble antipsoriatic drug apremilast (APM) in
any mono solvent or cosolvent mixtures with respect to temperature are not available in …
any mono solvent or cosolvent mixtures with respect to temperature are not available in …
Physicochemical characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated solid lipid nanoparticles
Rosuvastatin calcium (RCa) is a very efficient antihyperlipidemic agent, however, being a
BCS class II drug, results in poor oral bioavailability. The present study focused on the …
BCS class II drug, results in poor oral bioavailability. The present study focused on the …
Solubility of a poorly soluble immunosuppressant in different pure solvents: Measurement, correlation, thermodynamics and molecular interactions
The objective of this research work was to measure the solubility of mycophenolate mofetil
(MPM) in ten different pure solvents at temperatures T= 298.2 K to 318.2 K and pressure p …
(MPM) in ten different pure solvents at temperatures T= 298.2 K to 318.2 K and pressure p …
Hybrid Self‐Assembled Gel Beads for Tuneable pH‐Controlled Rosuvastatin Delivery
CC Piras, AK Patterson… - Chemistry–A European …, 2021 - Wiley Online Library
This article describes the fabrication of new pH‐responsive hybrid gel beads combining the
polymer gelator calcium alginate with two different low‐molecular‐weight gelators (LMWGs) …
polymer gelator calcium alginate with two different low‐molecular‐weight gelators (LMWGs) …
Solubility determination of raloxifene hydrochloride in ten pure solvents at various temperatures: Thermodynamics-based analysis and solute–solvent interactions
The purpose of the present study was to determine the solubility of raloxifene hydrochloride
(RHCl) in ten solvents: water, ethanol, isopropyl alcohol (IPA), ethylene glycol (EG) …
(RHCl) in ten solvents: water, ethanol, isopropyl alcohol (IPA), ethylene glycol (EG) …
Solubility measurement, thermodynamics and molecular interactions of flufenamic acid in different neat solvents
The solubility data of poorly soluble anti-inflammatory drug flufenamic acid (FFA) are scarce
in literature. Therefore, in the current study, the solubility of FFA in eleven different neat …
in literature. Therefore, in the current study, the solubility of FFA in eleven different neat …
Strategic design and clinical evaluation of a fixed-dose combination tablet comprising valsartan, amlodipine, rosuvastatin and ezetimibe for patients with hypertension …
Purpose The objective of this study was to design a fixed-dose combination (FDC) tablet
with minimal interaction of valsartan, amlodipine, rosuvastatin and ezetimibe to improve …
with minimal interaction of valsartan, amlodipine, rosuvastatin and ezetimibe to improve …
The use of Calcium Phosphate-based starter pellets for the preparation of Sprinkle IR MUPS formulation of Rosuvastatin Calcium
K Cal, B Mikolaszek, T Hess, M Papaioannou, J Lenik… - Pharmaceuticals, 2023 - mdpi.com
Sprinkle formulations represent an interesting concept of medicinal products aimed at the
steadily growing population of patients suffering from swallowing difficulties (dysphagia). In …
steadily growing population of patients suffering from swallowing difficulties (dysphagia). In …