DNA-m6A calling and integrated long-read epigenetic and genetic analysis with fibertools
Long-read DNA sequencing has recently emerged as a powerful tool for studying both
genetic and epigenetic architectures at single-molecule and single-nucleotide resolution …
genetic and epigenetic architectures at single-molecule and single-nucleotide resolution …
Examining chromatin heterogeneity through PacBio long-read sequencing of M.EcoGII methylated genomes: an m6A detection efficiency and calling bias correcting …
Recent studies have combined DNA methyltransferase footprinting of genomic DNA in
nuclei with long-read sequencing, resulting in detailed chromatin maps for multi-kilobase …
nuclei with long-read sequencing, resulting in detailed chromatin maps for multi-kilobase …
Maternal SMARCA5 is required for major ZGA in mouse embryos
ON Kubinyecz, D Drage, F Santos, C Krueger… - bioRxiv, 2023 - biorxiv.org
Zygotic genome activation (ZGA) in mice takes place in two waves, a minor wave in the one-
cell embryo, and a major wave at the two-cell stage, both accompanied by global …
cell embryo, and a major wave at the two-cell stage, both accompanied by global …
Sensitive multimodal profiling of native DNA by transposase-mediated single-molecule sequencing
We present SMRT-Tag: a multiplexable, PCR-free approach for constructing low-input,
single-molecule Pacific Biosciences (PacBio) sequencing libraries through Tn5 …
single-molecule Pacific Biosciences (PacBio) sequencing libraries through Tn5 …
The single-molecule accessibility landscape of newly replicated mammalian chromatin
We present replication-aware single-molecule accessibility map** (RASAM), a method to
nondestructively measure replication status and protein-DNA interactions on chromatin …
nondestructively measure replication status and protein-DNA interactions on chromatin …
Remodeling of higher order chromatin structures
P Vizjak - 2023 - edoc.ub.uni-muenchen.de
In fast allen Eukaryoten ist die DNA in einem dynamischen Polymer namens Chromatin
organisiert. Das Nukleosom, der elementare Baustein des Chromatins, besteht aus einem …
organisiert. Das Nukleosom, der elementare Baustein des Chromatins, besteht aus einem …