Biocatalysis has undergone revolutionary progress in the past century. Benefited by the
integration of multidisciplinary technologies, natural enzymatic reactions are constantly …

Betalains are water-soluble pigments present in vacuoles of plants of the order
Caryophyllales and in mushrooms of the genera Amanita, Hygrocybe and Hygrophorus …

Melanin is a common name for a group of biopolymers with the dominance of potential
applications in medical sciences, cosmeceutical, bioremediation, and bioelectronic …

Metabolic engineers endeavor to create a bio-based manufacturing industry using microbes
to produce fuels, chemicals, and medicines. Plant natural products (PNPs) are historically …

Metabolic burden is defined by the influence of genetic manipulation and environmental
perturbations on the distribution of cellular resources. The rewiring of microbial metabolism …

The production of bioactive plant compounds using microbial hosts is considered a safe,
cost-competitive and scalable approach to their production. However, microbial production …

Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of
complex molecules with diverse applications, from medicine to agriculture and materials …

Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

Anthocyanins, carotenoids, and betalains are known as the three major pigments in the
plant kingdom. Anthocyanins are flavonoids derived from the phenylpropanoid pathway …

The biosynthesis of natural products often requires eukaryotic cytochrome P450s (P450s) in
combination with P450 reductase, in physical proximity, to perform electron-transfer …