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History, discovery, and classification of lncRNAs
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
MicroRNA in control of gene expression: an overview of nuclear functions
C Catalanotto, C Cogoni, G Zardo - International journal of molecular …, 2016 - mdpi.com
The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a
sequence specific manner has had a massive impact on biology. Recent improvements in …
sequence specific manner has had a massive impact on biology. Recent improvements in …
Regulatory network of miRNA on its target: coordination between transcriptional and post-transcriptional regulation of gene expression
MicroRNAs (miRNAs) are a class of endogenous small noncoding RNAs that participate in a
majority of biological processes via regulating target gene expression. The post …
majority of biological processes via regulating target gene expression. The post …
Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer
H Liu, C Lei, Q He, Z Pan, D **ao, Y Tao - Molecular cancer, 2018 - Springer
MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22
nucleotides. They serve as key regulators in various biological processes and their …
nucleotides. They serve as key regulators in various biological processes and their …
The rise of regulatory RNA
Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …
suggests that RNA is not only functional as a messenger between DNA and protein but also …
The hallmarks of cancer: a long non-coding RNA point of view
T Gutschner, S Diederichs - RNA biology, 2012 - Taylor & Francis
With the advent of next generation sequencing methods and progress in transcriptome
analysis, it became obvious that the human genome contains much more than just protein …
analysis, it became obvious that the human genome contains much more than just protein …
Evolutionary conservation of long non-coding RNAs; sequence, structure, function
Background Recent advances in genomewide studies have revealed the abundance of long
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …
non-coding RNAs (lncRNAs) in mammalian transcriptomes. The ENCODE Consortium has …
The STAT3-binding long noncoding RNA lnc-DC controls human dendritic cell differentiation
P Wang, Y Xue, Y Han, L Lin, C Wu, S Xu, Z Jiang, J Xu… - Science, 2014 - science.org
Long noncoding RNAs (lncRNAs) play important roles in diverse biological processes;
however, few have been identified that regulate immune cell differentiation and function …
however, few have been identified that regulate immune cell differentiation and function …
The functional role of long non-coding RNA in human carcinomas
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …
demonstrating potential roles in both oncogenic and tumor suppressive pathways. These …
Long non-coding RNAs and cancer: a new frontier of translational research?
Tiling array and novel sequencing technologies have made available the transcription
profile of the entire human genome. However, the extent of transcription and the function of …
profile of the entire human genome. However, the extent of transcription and the function of …