[HTML][HTML] Convalescent plasma in Covid-19: Possible mechanisms of action

M Rojas, Y Rodríguez, DM Monsalve… - Autoimmunity …, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible of the
coronavirus disease 2019 (COVID-19) pandemic. Therapeutic options including …

IVIG-mediated effector functions in autoimmune and inflammatory diseases

C Galeotti, SV Kaveri, J Bayry - International immunology, 2017 - academic.oup.com
Intravenous immunoglobulin (IVIG) is a pooled preparation of normal IgG obtained from
several thousand healthy donors. It is widely used in the immunotherapy of a large number …

Differential antibody glycosylation in autoimmunity: sweet biomarker or modulator of disease activity?

M Seeling, C Brückner, F Nimmerjahn - Nature Reviews Rheumatology, 2017 - nature.com
A loss of humoral tolerance is a hallmark of many autoimmune diseases and the detection of
self-reactive antibodies (autoantibodies) of the immunoglobulin G (IgG) isotype is widely …

The role of antibody glycosylation in autoimmune and alloimmune kidney diseases

A Beyze, C Larroque, M Le Quintrec - Nature Reviews Nephrology, 2024 - nature.com
Immunoglobulin glycosylation is a pivotal mechanism that drives the diversification of
antibody functions. The composition of the IgG glycome is influenced by environmental …

Human mast cells and basophils—How are they similar how are they different?

G Varricchi, U Raap, F Rivellese… - Immunological …, 2018 - Wiley Online Library
Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …

Natural antibodies: from first-line defense against pathogens to perpetual immune homeostasis

MS Maddur, S Lacroix-Desmazes, JD Dimitrov… - Clinical Reviews in …, 2020 - Springer
Natural antibodies (nAbs) are most commonly defined as immunoglobulins present in the
absence of pathological conditions or deliberate immunizations. Occurrence of nAbs in germ …

Mechanisms of action of intravenous immunoglobulin

B Chaigne, L Mouthon - Transfusion and Apheresis Science, 2017 - Elsevier
Abstracts Taking advantage of the “World Apheresis Association/Société Française
d'Hémaphérèse” meeting held in Paris in April 2016, this article reviews the current …

Intravenous immunoglobulin: mechanism of action in autoimmune and inflammatory conditions

J Bayry, EA Ahmed, D Toscano-Rivero… - The Journal of Allergy …, 2023 - Elsevier
Intravenous immunoglobulin (IVIG) is the mainstay of therapy for humoral immune
deficiencies and numerous inflammatory disorders. Although the use of IVIG may be …

Protection in antibody-and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs

BM Fiebiger, J Maamary, A Pincetic… - Proceedings of the …, 2015 - National Acad Sciences
The antiinflammatory activity of intravenous immunoglobulin (IVIG) is dependent on the
presence of sialic acid in the core IgG fragment crystallizable domain (Fc) glycan, resulting …

Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy

M Das, A Karnam, E Stephen-Victor, L Gilardin… - Cell death & …, 2020 - nature.com
Autophagy plays an important role in the regulation of autoimmune and autoinflammatory
responses of the immune cells. Defective autophagy process is associated with various …