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Catalytic activities, molecular connections, and biological functions of plant RNA exosome complexes
H Lange, D Gagliardi - The Plant Cell, 2022 - academic.oup.com
RNA exosome complexes provide the main 3′–5′-exoribonuclease activities in eukaryotic
cells and contribute to the maturation and degradation of virtually all types of RNA. RNA …
cells and contribute to the maturation and degradation of virtually all types of RNA. RNA …
EXOSC5 maintains cancer stem cell activity in endometrial cancer by regulating the NTN4/integrin β1 signalling axis
YH Huang, WL Wang, PH Wang… - … journal of biological …, 2024 - pmc.ncbi.nlm.nih.gov
Endometrial carcinoma (EC) is a common type of uterine cancer in developed countries,
originating from the uterine epithelium. The incidence rate of EC in Taiwan has doubled from …
originating from the uterine epithelium. The incidence rate of EC in Taiwan has doubled from …
RNA degradation by the plant RNA exosome involves both phosphorolytic and hydrolytic activities
N Sikorska, H Zuber, A Gobert, H Lange… - Nature …, 2017 - nature.com
The RNA exosome provides eukaryotic cells with an essential 3′–5′ exoribonucleolytic
activity, which processes or eliminates many classes of RNAs. Its nine-subunit core (Exo9) is …
activity, which processes or eliminates many classes of RNAs. Its nine-subunit core (Exo9) is …
RNA exosomes and their cofactors
C Kilchert - The Eukaryotic RNA Exosome: Methods and Protocols, 2020 - Springer
The RNA exosome is a ribonucleolytic multiprotein complex that is conserved and essential
in all eukaryotes. Although we tend to speak of “the” exosome complex, it should be more …
in all eukaryotes. Although we tend to speak of “the” exosome complex, it should be more …
Structure and function of TatD exonuclease in DNA repair
TatD is an evolutionarily conserved protein with thousands of homologues in all kingdoms of
life. It has been suggested that TatD participates in DNA fragmentation during apoptosis in …
life. It has been suggested that TatD participates in DNA fragmentation during apoptosis in …
EXOSC5 as a novel prognostic marker promotes proliferation of colorectal cancer via activating the ERK and AKT pathways
H Pan, J Pan, S Song, L Ji, H Lv, Z Yang - Frontiers in oncology, 2019 - frontiersin.org
Background and Objective: Exosome component 5 (EXOSC5) is a novel cancer-related
gene that is aberrantly expressed in various malignances. However, the molecular …
gene that is aberrantly expressed in various malignances. However, the molecular …
[HTML][HTML] Genome-Wide Analysis of the RNase T2 Family and Identification of Interacting Proteins of Four ClS-RNase Genes in '**angShui' Lemon
YZ Li, JW Zhu, W Lin, MY Lan, C Luo, LM **a… - International Journal of …, 2022 - mdpi.com
S-RNase plays vital roles in the process of self-incompatibility (SI) in Rutaceae plants. Data
have shown that the rejection phenomenon during self-pollination is due to the degradation …
have shown that the rejection phenomenon during self-pollination is due to the degradation …
The exozyme model: a continuum of functionally distinct complexes
Exosome complexes are composed of 10 to 11 subunits and are involved in multiple facets
of 3′→ 5′ RNA processing and turnover. The current paradigm stipulates that a uniform …
of 3′→ 5′ RNA processing and turnover. The current paradigm stipulates that a uniform …
Endonucleases and apoptosis in animals
NI Aleksandrushkina, BF Vanyushin - Biochemistry (Moscow), 2012 - Springer
Endonucleases are the main instruments of obligatory DNA degradation in apoptosis. Many
endonucleases have marked processive action; initially they split DNA in chromatin into very …
endonucleases have marked processive action; initially they split DNA in chromatin into very …
Polyadenylated versions of small non-coding RNAs in Saccharomyces cerevisiae are degraded by Rrp6p/Rrp47p independent of the core nuclear exosome
In Saccharomyces cerevisiae, polyadenylated forms of mature (and not precursor) small non-
coding RNAs (sncRNAs) those fail to undergo proper 3′-end maturation are subject to an …
coding RNAs (sncRNAs) those fail to undergo proper 3′-end maturation are subject to an …