Natural product synthesis is a highly demanding field in constant need of efficient
transformations that allow either straightforward, scalable, and high-yielding preparation of …

In the last decade, a number of methods using various copper complexes and salts to carry
out cross-coupling reactions leading to the formation of Cheteroatom (CN, CO, CS, CP …

Alkynes represent one of the most important and versatile building blocks in organic
synthesis. Heteroatom-substituted alkynes, which can be considered as subgroups of …

Ynamides are unique alkynes with a carbon–carbon triple bond directly attached to the
nitrogen atom bearing an electron-withdrawing group. The alkyne is strongly polarized by …

Ynamides display an exceptionally fine balance between stability and reactivity. They also
offer unique and multiple opportunities for the inclusion of nitrogen‐based functionalities into …

The utility of copper-mediated cross-coupling reactions has been significantly increased by
the development of mild reaction conditions and the ability to employ catalytic amounts of …

The C–N cross-coupling chemistry intensely developed since the late 1990s has supplied
synthesists with an overwhelming number of methods to effectively combine carbon and …

The chemistry of the carbonyl group is essential to modern organic synthesis. The
preparation of substituted, enantioenriched 1, 3-or 1, 5-dicarbonyls is well developed, as …

Metal–organic frameworks have recently attracted attention as heterogeneous catalysts due
to their high content of metal centres and large surface area and pore volume, along with …

In addition to the well-established nucleophilic alkynylation, the use of electrophilic alkynes
can expand tremendously the scope of acetylene transfer reactions. The use of metal …