Perinatal group B streptococcal infections: virulence factors, immunity, and prevention strategies
Group B streptococcus (GBS) or Streptococcus agalactiae is a β-hemolytic, Gram-positive
bacterium that is a leading cause of neonatal infections. GBS commonly colonizes the lower …
bacterium that is a leading cause of neonatal infections. GBS commonly colonizes the lower …
Bacterial and host determinants of group B streptococcal vaginal colonization and ascending infection in pregnancy
A Brokaw, A Furuta, M Dacanay… - Frontiers in cellular …, 2021 - frontiersin.org
Group B streptococcus (GBS) is a gram-positive bacteria that asymptomatically colonizes the
vaginal tract. However, during pregnancy maternal GBS colonization greatly predisposes …
vaginal tract. However, during pregnancy maternal GBS colonization greatly predisposes …
Extracellular Vesicles-mediated recombinant IL-10 protects against ascending infection-associated preterm birth by reducing fetal inflammatory response
Background Fetal inflammatory response mediated by the influx of immune cells and
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
activation of pro-inflammatory transcription factor NF-κB in feto-maternal uterine tissues is …
Human β‐defensin‐1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra‐amniotic infection
Problem Human β‐defensins (HBD s) are antimicrobial peptides that participate in the
soluble innate immune mechanisms against infection. Herein, we determined whether HBD …
soluble innate immune mechanisms against infection. Herein, we determined whether HBD …
Sex-specific maternofetal innate immune responses triggered by group B Streptococci
Abstract Group B Streptococcus (GBS) is one of the most common bacteria isolated in
human chorioamnionitis, which is a major risk factor for premature birth and brain injuries …
human chorioamnionitis, which is a major risk factor for premature birth and brain injuries …
miRNA‐126 enhances viability, colony formation, and migration of keratinocytes HaCaT cells by regulating PI3 K/AKT signaling pathway
L Chang, J Liang, X **a, X Chen - Cell biology international, 2019 - Wiley Online Library
Wound healing is a basic biological process including proliferation and migration of
keratinocyte. The effects of microRNAs on skin wound healing remain largely unexplored …
keratinocyte. The effects of microRNAs on skin wound healing remain largely unexplored …
Decidual stromal cell‐derived PGE2 regulates macrophage responses to microbial threat
LM Rogers, AP Anders, RS Doster… - American journal of …, 2018 - Wiley Online Library
Problem Bacterial chorioamnionitis causes adverse pregnancy outcomes, yet host‐microbial
interactions are not well characterized within gestational membranes. The decidua, the …
interactions are not well characterized within gestational membranes. The decidua, the …
Effect of MicroRNA-146a modified adipose-derived stem cell exosomes on rat back wound healing
G Chen, MD, Y Wu, MD, L Zou, MD… - … Journal of Lower …, 2023 - journals.sagepub.com
Objective: To investigate the effect of MicroRNA-146a modified adipose-derived stem cell
exosomes on the proliferation and migration of fibroblasts and the therapeutic effect on …
exosomes on the proliferation and migration of fibroblasts and the therapeutic effect on …
Frontiers in the etiology and treatment of preterm premature rupture of membrane: from molecular mechanisms to innovative therapeutic strategies
L Xu, T Yang, M Wen, D Wen, C **, M An, L Wang… - Reproductive …, 2024 - Springer
Preterm premature rupture of membranes (pPROM) poses a significant threat to fetal viability
and increases the risk for newborn morbidities. The perinatal period of preterm infants …
and increases the risk for newborn morbidities. The perinatal period of preterm infants …
Protein kinase D mediates inflammatory responses of human placental macrophages to Group B Streptococcus
JA Sutton, LM Rogers, BREA Dixon… - American Journal of …, 2019 - Wiley Online Library
Problem During pregnancy, Group B Streptococcus (GBS) can infect fetal membranes to
cause chorioamnionitis, resulting in adverse pregnancy outcomes. Macrophages are the …
cause chorioamnionitis, resulting in adverse pregnancy outcomes. Macrophages are the …