In 1976 Ebola revealed itself to the world, marking the beginning of a series of localized
outbreaks. However, it was the Ebola outbreak that began in 2013 that incited fear and …

One of the actively develo** areas of drug development is the creation of chimeric toxins,
recombinant bifunctional molecules designed to affect target cells selectively. The prevalent …

Ebola virus (EBOV), a member of the Filoviridae family, causes EBOV disease (EVD), a
highly fatal and neglected tropical disease (NTD). Despite its severity, treatment options …

Infectious diarrhea kills more children each day than AIDS, malaria, and measles combined
[1]. In humans, the leading causes of virally induced diarrhea include rotavirus, norovirus …

Ebola virus (EBOV) is a zoonotic virus comprising of six known different species, designated
within the family Filoviridae and genus Ebolavirus. The first recorded outbreak of an EBOV …

Viral infection is found in approximately 30% of all sepsis cases and may be followed by
bacterial infection in organs such as the lungs. Sepsis manifests as fever, hemorrhagic …

Viroporins are virus-encoded proteins that mediate ion channel (IC) activity, playing critical
roles in virus entry, replication, pathogenesis, and immune evasion. Previous studies have …

Ebola virus (EBOV) causes lethal hemorrhagic fevers with case fatality rates of up to 90%.
Outbreaks are sporadic and unpredictable, and vaccination has been key to controlling …

Enterotoxigenic Escherichia coli (ETEC) STb toxin exhibits striking structural similarity to
Ebola virus (EBOV) delta peptide. Both ETEC and EBOV delta peptide are enterotoxins …

Viruses initiate infection of host cells by entering through a variety of different pathways.
Their entry is concluded by the release of the viral genome into the cytoplasm, where the …