Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Skeletal muscle extracellular matrix–what do we know about its composition, regulation, and physiological roles? A narrative review

R Csapo, M Gumpenberger, B Wessner - Frontiers in physiology, 2020 - frontiersin.org
Skeletal muscle represents the largest body-composition component in humans. In addition
to its primary function in the maintenance of upright posture and the production of …

[HTML][HTML] Stimuli and sensors that initiate skeletal muscle hypertrophy following resistance exercise

H Wackerhage, BJ Schoenfeld… - Journal of applied …, 2019 - journals.physiology.org
One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that
occurs in response to resistance exercise. A large body of work shows that a mammalian …

Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

E Espino-Gonzalez, E Dalbram, R Mounier, J Gondin… - Cell Metabolism, 2024 - cell.com
Diabetes represents a major public health concern with a considerable impact on human life
and healthcare expenditures. It is now well established that diabetes is characterized by a …

Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations

MV Franchi, ND Reeves, MV Narici - Frontiers in physiology, 2017 - frontiersin.org
Skeletal muscle contracts either by shortening or lengthening (concentrically or
eccentrically, respectively); however, the two contractions substantially differ from one …

An evidence-based narrative review of mechanisms of resistance exercise–induced human skeletal muscle hypertrophy

C Lim, EA Nunes, BS Currier… - … and science in …, 2022 - pmc.ncbi.nlm.nih.gov
Skeletal muscle plays a critical role in physical function and metabolic health. Muscle is a
highly adaptable tissue that responds to resistance exercise (RE; loading) by …

Muscle thickness correlates to muscle cross‐sectional area in the assessment of strength training‐induced hypertrophy

MV Franchi, S Longo, J Mallinson… - … journal of medicine …, 2018 - Wiley Online Library
Muscle thickness (MT) measured by ultrasound has been used to estimate cross‐sectional
area (measured by CT and MRI) at a single time point. We tested whether MT could be used …

A critical evaluation of the biological construct skeletal muscle hypertrophy: size matters but so does the measurement

CT Haun, CG Vann, BM Roberts, AD Vigotsky… - Frontiers in …, 2019 - frontiersin.org
Skeletal muscle is highly adaptable and has consistently been shown to morphologically
respond to exercise training. Skeletal muscle growth during periods of resistance training …

Resistance training‐induced changes in integrated myofibrillar protein synthesis are related to hypertrophy only after attenuation of muscle damage

F Damas, SM Phillips, CA Libardi… - The Journal of …, 2016 - Wiley Online Library
Key points Skeletal muscle hypertrophy is one of the main outcomes from resistance training
(RT), but how it is modulated throughout training is still unknown. We show that changes in …