A vaccine based on outer membrane vesicles of pertussis (omvPV) is protective in a mouse-
challenge model and induces a broad antibody and mixed Th1/Th2/Th17 response against …

Pertussis ('whoo** cough') is a severe respiratory tract infection that primarily affects
young children and unimmunised infants. Despite widespread vaccine coverage, it remains …

Whoo** cough, or pertussis, mostly caused by Bordetella pertussis, is a respiratory
disease that affects all age groups, but severe and fatal pertussis occurs almost exclusively …

In our previous study, several iron-related outer membrane proteins in Aeromonas
hydrophila, a serious pathogen of farmed fish, conferred high immunoprotectivity to fish, and …

Bacterial small RNAs (sRNAs) posttranscriptionally regulate gene expressions involved in
various biological processes, including pathogenicity. Our previous study identified sRNAs …

Acellular multivalent vaccines for pertussis (DTaP and Tdap) prevent symptomatic disease
and infant mortality, but immunity to Bordetella pertussis infection wanes significantly over …

Brucella enters their hosts mostly through mucosae from where it spreads systemically.
Adhesion to extracellular matrix (ECM) components or to host cells is important for the …

Bordetella pertussis, the bacterium responsible for whoo** cough, remains a significant
public health challenge despite the existing licensed pertussis vaccines. Current acellular …

The limited protective immunity induced by acellular pertussis vaccines demands
development of novel vaccines that induce broader and longer-lived immunity. In this study …

Well-adapted pathogens have evolved to survive the many challenges of a robust immune
response. Defending against all host antimicrobials simultaneously would be exceedingly …