A human immunodeficiency virus type-1 (HIV-1) vaccine which is able to effectively prevent
infection would be the most powerful method of extinguishing pandemic of the acquired …

Hydrocarbon stapling can restore bioactive α-helical structure to natural peptides, yielding
research tools and prototype therapeutics to dissect and target protein interactions. Here we …

The membrane-proximal external region (MPER) of the human immunodeficiency virus, type
1 (HIV-1) envelope glycoprotein subunit gp41 is targeted by potent broadly neutralizing …

Develo** a vaccine that overcomes the diversity of HIV-1 is likely to require a strategy that
directs antibody (Ab) responses toward conserved regions of the viral Envelope (Env) …

Flagellin's potential as a vaccine adjuvant has been increasingly explored over the last three
decades. Monomeric flagellin proteins are the only known agonists of Toll-like receptor 5 …

The HIV-1 membrane proximal external region (MPER) that is targeted by several broadly
neutralizing antibodies (BNAbs) has been considered a potential immunogen for vaccine …

The interaction between the Bim BH3 peptide and the viral protein BHRF1 is pivotal to
understanding the fundamental molecular details of the mechanism used by the Epstein …

The C-terminal alpha-helix of gp41 membrane-proximal external region (MPER; 671
NWFDITNWLWYIK 683) encompassing 4E10/10E8 epitopes is an attractive target for HIV-1 …

The membrane-proximal external region (MPER) of HIV-1 gp41 is an attractive target for
vaccine development. Thus, better understanding of its immunogenic properties in various …

Constructing a vaccine against HIV-1, able to induce production of broadly neutralizing
antibodies, is crucial. We report here the selection and characterization of …