Aims Concerns exist regarding the cardiovascular safety of domperidone. However, many of
the previous studies addressing this issue had important limitations. We aimed to examine …

Introduction: There are concerns that opioids may be associated with an increased risk of
infection. This safety issue is alarming given the widespread use of opioids in pain …

Background Fluid retention and endothelial dysfunction have been related to use of
nonsteroidal anti-inflammatory drugs (NSAIDs), and type 2 diabetes mellitus (T2DM) has …

Importance Gabapentin prescriptions have drastically increased in the US due to off-label
prescribing in settings such as opioid use disorder (OUD) treatment to manage a range of …

Importance Stimulant medication use is common among individuals receiving
buprenorphine for opioid use disorder (OUD). Associations between prescription stimulant …

Importance Persons with opioid use disorder (OUD) and co-occurring alcohol use disorder
(AUD) are understudied and undertreated. It is unknown whether the use of medications to …

Background Opioid-overdose deaths are associated with poisoning with prescription and
illicit opioids in the USA. In contrast, opioid-related deaths (ORDs) in the UK often involve …

Abstract Background/Objectives Unintentional falls are a leading cause of injury for older
adults, and evidence is needed to understand modifiable risk factors. We evaluated 1‐year …

Importance The increased use of gabapentinoids has been most pronounced in older
people who are also susceptible to hip fractures. Objective To investigate the overall …

Background Observational studies have suggested an increased risk of intracranial
hemorrhage (ICH) associated with selective serotonin reuptake inhibitors (SSRIs) and other …