The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Silk fibroin (SF) is a fibrous protein which is produced mainly by silkworms and spiders. Its
unique mechanical properties, tunable biodegradation rate and the ability to support the …

Tissue engineering is currently limited by the inability to adequately vascularize tissues in
vitro or in vivo. Issues of nutrient perfusion and mass transport limitations, especially oxygen …

The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

For 3D bioprinted tissues to be scaled-up to clinically relevant sizes, effective
prevascularisation strategies are required to provide the necessary nutrients for normal …

Scaffolds that couple electrical and elastic properties may be valuable for cardiac cell
function. However, existing conductive materials do not mimic physiological properties. We …

Biochemical analysis is crucial in understanding mechanism of life activities and giving
biological insights into life process. With inherent merits in flexible design, microscale of …

Recent advances in microfluidics have brought forth new tools for studying flow-induced
effects on mammalian cells, with important applications in cardiovascular, bone and cancer …

Osteogenic differentiation and mineralization of bone marrow stromal (BMS) cells depends
on the cells' interactions with bioactive peptides associated with the matrix proteins. The …

In complex organisms, cells are often dependent on their extracellular matrix (ECM) for
structural integrity, the mechanical properties of tissues, and for signaled regulation of …