Cardamonin: A new player to fight cancer via multiple cancer signaling pathways

J Nawaz, A Rasul, MA Shah, G Hussain, A Riaz… - Life sciences, 2020 - Elsevier
Nature's pharmacy has undoubtedly served humans as an affordable and safer health-care
regime for a long times. Cardamonin, a chalconoid present in several plants has been …

Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer

P Zhao, J Qiu, C Pan, Y Tang, M Chen, H Song, J Yang… - Phytomedicine, 2023 - Elsevier
Background Breast cancer is the most prevalent cancer worldwide, with high morbidity and
mortality. Despite great advances in the therapeutic strategies, the survival rate in the past …

Curcumol inhibits ferritinophagy to restrain hepatocyte senescence through YAP/NCOA4 in non‐alcoholic fatty liver disease

X Qi, A Song, M Ma, P Wang, X Zhang, C Lu… - Cell …, 2021 - Wiley Online Library
Objectives In recent years, cellular senescence has attracted a lot of interest in researchers
due to its involvement in non‐alcoholic fatty liver disease (NAFLD). However, the …

Curcumol suppresses CCF-mediated hepatocyte senescence through blocking LC3B–lamin B1 interaction in alcoholic fatty liver disease

X Qi, S Zheng, M Ma, N Lian, H Wang… - Frontiers in …, 2022 - frontiersin.org
Recent studies indicated that hepatocyte senescence plays an important role in the
development of alcoholic fatty liver disease (AFLD), suggesting that inhibition of hepatocyte …

Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR‐7/m‐TOR/SREBP1 pathway on prostate cancer

W Xu, J Ding, B Li, T Sun, X You, Q He, W Sheng - Biofactors, 2023 - Wiley Online Library
This study aimed to investigate the effects and underlying molecular mechanisms of icariin
(ICA) and curcumol on autophagy, ferroptosis, and lipid metabolism in prostate cancer …

Curcumol inhibits the expression of programmed cell death-ligand 1 through crosstalk between hypoxia-inducible factor-1α and STAT3 (T705) signaling pathways in …

HX Zuo, Y **, Z Wang, MY Li, ZH Zhang… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Curcuma wenyu** is a Chinese traditional herbal
medicine that is commonly used as an anti-oxidant, anti-proliferative, and anti-tumorigenic …

Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway

S Sun, S Huan, Z Li, Y Yao, Y Su, S **a, S Wang, X Xu… - PeerJ, 2022 - peerj.com
Liver fibrosis is a repair response process after chronic liver injury. During this process,
activated hepatic stellate cells (HSCs) will migrate to the injury site and secrete extracellular …

Curcumol ameliorates neuroinflammation after cerebral ischemia–reperfusion injury via affecting microglial polarization and Treg/Th17 balance through Nrf2/HO-1 …

Y Liu, W Wang, B Di, J Miao - Cell Death Discovery, 2024 - nature.com
Neuroinflammation caused by microglia and other immune cells plays pivotal role in
cerebral ischemia/reperfusion injury and recovery. Modulating microglial polarization or …

Investigation on the mechanisms by which the herbal remedies induce anti-prostate cancer activity: uncovering the most practical natural compound

A Poustforoosh, S Faramarz… - Journal of …, 2024 - Taylor & Francis
Prostate cancer (PCa) is one of the most reported cancers among men worldwide. Targeting
the essential proteins associated with PCa could be a promising method for cancer …

[HTML][HTML] Therapeutic potential of Curcuma oil and its terpenoids in gynecological cancers

Y Zhang, F Peng, C Yu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Background Gynecological cancers encompass all uncontrolled and aberrant cell growth in
the female reproductive system, therapeutic interventions are constantly evolving, but there …