Biomarkers for depression: recent insights, current challenges and future prospects
A plethora of research has implicated hundreds of putative biomarkers for depression, but
has not yet fully elucidated their roles in depressive illness or established what is abnormal …
has not yet fully elucidated their roles in depressive illness or established what is abnormal …
[HTML][HTML] How electroconvulsive therapy works?: understanding the neurobiological mechanisms
A Singh, SK Kar - Clinical Psychopharmacology and Neuroscience, 2017 - ncbi.nlm.nih.gov
Electroconvulsive therapy (ECT) is a time tested treatment modality for the management of
various psychiatric disorders. There have been a lot of modifications in the techniques of …
various psychiatric disorders. There have been a lot of modifications in the techniques of …
Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders
The literature on non-genetic peripheral biomarkers for major mental disorders is broad, with
conflicting results. An umbrella review of meta-analyses of non-genetic peripheral …
conflicting results. An umbrella review of meta-analyses of non-genetic peripheral …
Biology of GDNF and its receptors—relevance for disorders of the central nervous system
CF Ibáñez, JO Andressoo - Neurobiology of disease, 2017 - Elsevier
A targeted effort to identify novel neurotrophic factors for midbrain dopaminergic neurons
resulted in the isolation of GDNF (glial cell line-derived neurotrophic factor) from the …
resulted in the isolation of GDNF (glial cell line-derived neurotrophic factor) from the …
Melatonergic receptors (Mt1/Mt2) as a potential additional target of novel drugs for depression
A complex pathogenesis involving several physiological systems is theorized to underline
the development of depressive disorders. Depression is accompanied by circadian …
the development of depressive disorders. Depression is accompanied by circadian …
Neurotrophic factors (BDNF and GDNF) and the serotonergic system of the brain
NK Popova, TV Ilchibaeva, VS Naumenko - Biochemistry (Moscow), 2017 - Springer
Neurotrophic factors play a key role in development, differentiation, synaptogenesis, and
survival of neurons in the brain as well as in the process of their adaptation to external …
survival of neurons in the brain as well as in the process of their adaptation to external …
Value of peripheral neurotrophin levels for the diagnosis of depression and response to treatment: a systematic review and meta-analysis
Y Shi, D Luan, R Song, Z Zhang - European Neuropsychopharmacology, 2020 - Elsevier
The neurotrophin hypothesis indicates that neurotrophic factors are important for the
pathophysiology of major depressive disorder (MDD), with alterations in peripheral …
pathophysiology of major depressive disorder (MDD), with alterations in peripheral …
Molecular biomarkers of depression
Depression is the leading psychiatric disorder worldwide with a significant economic and
emotional strain on society. There is a need for robust biomarkers which will help improve …
emotional strain on society. There is a need for robust biomarkers which will help improve …
Neurobiological highlights of cognitive impairment in psychiatric disorders
This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …
major component of the disease, influencing life quality. There are plenty of data proving that …
Role of trophic factors GDNF, IGF-1 and VEGF in major depressive disorder: A comprehensive review of human studies
AN Sharma, JC Soares, AF Carvalho… - Journal of affective …, 2016 - Elsevier
Rationale The neurotrophin hypothesis of major depressive disorder (MDD) postulates that
this illness results from aberrant neurogenesis in brain regions that regulates emotion and …
this illness results from aberrant neurogenesis in brain regions that regulates emotion and …